Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CDK7 | P50613 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | CCNH | P51946 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8025504 | 0.83 | — | — | |
| SCHEMBL8558706 | 0.73 | ALDH1A1 (0.41) | — | |
| SCHEMBL30567305 | 0.72 | ALDH1A1 (0.52) | — | |
| SCHEMBL170860 | 0.72 | ALDH1A1 (0.52) | — | |
| Sulfamide SCHEMBL9442883 | 0.70 | METAP2 (0.30) | — | |
| SCHEMBL29738719 | 0.69 | CYP1A2 (0.38) | CYP1A2CYP2C19HSD17B10CCNT1CDK1 | |
| SCHEMBL9150950 | 0.68 | — | — | |
| SCHEMBL9995236 | 0.64 | — | — | |
| SCHEMBL22725531 | 0.64 | AGTR1 (0.30) | — | |
| SCHEMBL5242679 | 0.64 | CDK2 (0.32) | CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105399746-A | Triazolopyrimidinylsulfonamide compound, composition containing compound, and application of compound | HEILONGJIANG KAIAO TECH DEV CO LTD | 2016-03-16 | — | — | CN | disclosed |
| CN-105399746-A | Triazolopyrimidinylsulfonamide compound, composition containing compound, and application of compound | HEILONGJIANG KAIAO TECH DEV CO LTD | 2016-03-16 | — | — | CN | disclosed |