SCHEMBL8025504

SCHEMBL8025504

O=S(=O)(Cl)c1ncc2[nH]nnc2n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8558706 0.73 ALDH1A1 (0.41)
SCHEMBL19741076 0.70 METAP2 (0.30)
SCHEMBL170860 0.68 ALDH1A1 (0.52)
SCHEMBL9150950 0.68
SCHEMBL11500740 0.66 ALDH1A1 (0.36)
SCHEMBL19131845 0.64
SCHEMBL22725531 0.64 AGTR1 (0.30)
SCHEMBL5242679 0.64 CDK2 (0.32)
SCHEMBL9995236 0.64
Sulfamide SCHEMBL9442883 0.63 METAP2 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6162915-A Process for heterocyclic sulfonyl chloride compounds DOW AGROSCIENCES LLC (US) 2000-12-19 US claimed
CN-1230961-A Heterocyclic sulfonyl chloride compounds DOW AGROSCIENCES LLC (US) 1999-10-06 CN claimed
EP-0922047-A1 PROCESS FOR HETEROCYCLIC SULFONYL CHLORIDE COMPOUNDS Dow AgroSciences LLC (US) 1999-06-16 EP claimed
WO-1999000392-A1 PROCESS FOR HETEROCYCLIC SULFONYL CHLORIDE COMPOUNDS DOW AGROSCIENCES LLC (US) 1999-01-07 WO claimed
EP-0434624-B1 Triazolylsulfonamides CIBA GEIGY AG (CH) 1995-02-08 EP claimed
EP-0434624-A1 Triazolylsulfonamides CIBA-GEIGY AG (CH) 1991-06-26 EP claimed
US-6162915-A Process for heterocyclic sulfonyl chloride compounds DOW AGROSCIENCES LLC (US) 2000-12-19 US disclosed
CN-1230961-A Heterocyclic sulfonyl chloride compounds DOW AGROSCIENCES LLC (US) 1999-10-06 CN disclosed
EP-0537611-B1 Process for the preparation of substituted N-(aryl)-1,2,4-triazolopyrimidine-2-sulfonamides DOW AGROSCIENCES LLC (US) 1998-08-12 EP disclosed
US-5217521-A Preemergence, postemergence herbicides CIBA-GEIGY CORPORATION (US) 1993-06-08 US disclosed