Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | IL1RN | P18510 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 4/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SGK1 | O00141 | 3/20 | 0.34 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28050244 | 0.73 | CYP1A2 (0.36) | — | |
| SCHEMBL8025504 | 0.73 | — | — | |
| SCHEMBL9536716 | 0.67 | HPGDS (0.44) | ALDH1A1KMT2AMEN1MAPTMAPK1 | |
| SCHEMBL6431253 | 0.67 | KEAP1 (0.57) | ALDH1A1IL1RNKEAP1ERAP1KMT2A | |
| SCHEMBL4070253 | 0.67 | ALDH1A1 (0.46) | ALDH1A1KMT2A | |
| SCHEMBL5227239 | 0.65 | GAA (0.50) | ALDH1A1IL1RNKEAP1ERAP1KMT2A | |
| SCHEMBL16045960 | 0.65 | KEAP1 (0.53) | ALDH1A1IL1RNKEAP1ERAP1KMT2A | |
| SCHEMBL8558704 | 0.62 | KEAP1 (0.42) | ALDH1A1IL1RNKEAP1ERAP1KMT2A | |
| SCHEMBL10546861 | 0.62 | TSHR (0.50) | ALDH1A1IL1RNKEAP1ERAP1KMT2A | |
| SCHEMBL6203448 | 0.61 | SYK (0.53) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537611-B1 | Process for the preparation of substituted N-(aryl)-1,2,4-triazolopyrimidine-2-sulfonamides | DOW AGROSCIENCES LLC (US) | 1998-08-12 | — | — | EP | disclosed |
| EP-0434624-B1 | Triazolylsulfonamides | CIBA GEIGY AG (CH) | 1995-02-08 | — | — | EP | disclosed |
| US-5217521-A | Preemergence, postemergence herbicides | CIBA-GEIGY CORPORATION (US) | 1993-06-08 | — | — | US | disclosed |
| US-5217521-A | Preemergence, postemergence herbicides | CIBA-GEIGY CORPORATION (US) | 1993-06-08 | — | — | US | disclosed |
| EP-0434624-A1 | Triazolylsulfonamides | CIBA-GEIGY AG (CH) | 1991-06-26 | — | — | EP | disclosed |
| EP-0434624-A1 | Triazolylsulfonamides | CIBA-GEIGY AG (CH) | 1991-06-26 | — | — | EP | disclosed |