Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23148487 | 0.85 | MAPT (0.61) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL28051135 | 0.85 | HTT (0.52) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL28252795 | 0.83 | HTT (0.50) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL6343830 | 0.80 | MEN1 (0.67) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL6342356 | 0.78 | HTT (0.46) | MEN1KMT2ALMNAALDH1A1HTT | |
| SCHEMBL6342525 | 0.76 | ALDH1A1 (0.68) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL148001 | 0.75 | MAPT (0.85) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL29539965 | 0.75 | MAPT (0.85) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL28051137 | 0.73 | HTT (0.61) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL6340645 | 0.72 | TUBB4A (0.56) | MAPTLMNAALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105287388-B | High dispersive carbazole sulfonamide derivative and preparation method thereof | 山西普德药业有限公司 | 2019-09-17 | — | — | CN | claimed |
| CN-105418487-A | Carbazole sulfonamide derivative eutectic and preparation method thereof | SHANXI PUDE PHARMACEUTICS CO LTD | 2016-03-23 | — | — | CN | claimed |
| CN-105287388-A | High-dispersion carbazole sulfonamide derivatives and preparation method thereof | SHANXI PUDE PHARMACEUTICS CO LTD | 2016-02-03 | — | — | CN | claimed |
| CN-105287388-B | High dispersive carbazole sulfonamide derivative and preparation method thereof | 山西普德药业有限公司 | 2019-09-17 | — | — | CN | disclosed |
| CN-105418487-A | Carbazole sulfonamide derivative eutectic and preparation method thereof | SHANXI PUDE PHARMACEUTICS CO LTD | 2016-03-23 | — | — | CN | disclosed |
| CN-105287388-A | High-dispersion carbazole sulfonamide derivatives and preparation method thereof | SHANXI PUDE PHARMACEUTICS CO LTD | 2016-02-03 | — | — | CN | disclosed |