Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 7/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HBB | P68871 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23148487 | 0.88 | MAPT (0.61) | HTTSMN1; SMN2MAPTTHRBTP53 | |
| SCHEMBL28252795 | 0.85 | HTT (0.50) | HTTSMN1; SMN2MAPTTHRBTP53 | |
| SCHEMBL28051139 | 0.85 | MEN1 (0.51) | HTTSMN1; SMN2MAPTTHRBTP53 | |
| SCHEMBL28298620 | 0.83 | HTT (0.57) | HTTSMN1; SMN2MAPTTHRBTP53 | |
| SCHEMBL6350411 | 0.79 | HTR6 (0.65) | HTTSMN1; SMN2MAPTTHRBTP53 | |
| SCHEMBL28051137 | 0.76 | HTT (0.61) | HTTSMN1; SMN2MAPTTHRBTP53 | |
| SCHEMBL6340701 | 0.75 | SMN1; SMN2 (0.49) | HTTSMN1; SMN2MAPTTHRBTP53 | |
| SCHEMBL6340645 | 0.75 | TUBB4A (0.56) | HTTSMN1; SMN2MAPTTHRBTP53 | |
| SCHEMBL2215125 | 0.74 | CA1 (0.62) | HTTSMN1; SMN2MAPTTHRBTP53 | |
| Hydrochloric Acid SCHEMBL6339594 | 0.73 | CA1 (0.61) | HTTSMN1; SMN2MAPTTHRBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105287388-B | High dispersive carbazole sulfonamide derivative and preparation method thereof | 山西普德药业有限公司 | 2019-09-17 | — | — | CN | claimed |
| CN-105418487-B | Carbazole sulfonamide derivative eutectic and preparation method thereof | 山西普德药业有限公司 | 2018-11-02 | — | — | CN | claimed |
| CN-105418487-A | Carbazole sulfonamide derivative eutectic and preparation method thereof | SHANXI PUDE PHARMACEUTICS CO LTD | 2016-03-23 | — | — | CN | claimed |
| CN-105287388-A | High-dispersion carbazole sulfonamide derivatives and preparation method thereof | SHANXI PUDE PHARMACEUTICS CO LTD | 2016-02-03 | — | — | CN | claimed |
| CN-105287388-B | High dispersive carbazole sulfonamide derivative and preparation method thereof | 山西普德药业有限公司 | 2019-09-17 | — | — | CN | disclosed |
| CN-105418487-B | Carbazole sulfonamide derivative eutectic and preparation method thereof | 山西普德药业有限公司 | 2018-11-02 | — | — | CN | disclosed |
| CN-105418487-A | Carbazole sulfonamide derivative eutectic and preparation method thereof | SHANXI PUDE PHARMACEUTICS CO LTD | 2016-03-23 | — | — | CN | disclosed |
| CN-105287388-A | High-dispersion carbazole sulfonamide derivatives and preparation method thereof | SHANXI PUDE PHARMACEUTICS CO LTD | 2016-02-03 | — | — | CN | disclosed |