Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL308403 | 0.94 | ALDH1A1 (0.47) | HSD17B10ACHEALDH1A1GLAMAPT | |
| Chloromethane SCHEMBL28051667 | 0.92 | HSD17B10 (0.43) | HSD17B10ACHEALDH1A1GLAMAPT | |
| SCHEMBL11163286 | 0.82 | MAPT (0.49) | HSD17B10ACHEALDH1A1MAPTPOLB | |
| SCHEMBL3179819 | 0.74 | HSPB1 (0.56) | ALDH1A1MAPTPOLBL3MBTL1LMNA | |
| Fluoromethane SCHEMBL28260001 | 0.73 | HSD17B10 (0.61) | HSD17B10ACHEALDH1A1MAPTPOLB | |
| SCHEMBL11153190 | 0.72 | MAPT (0.56) | MAPTPOLBTDP1TSHRLMNA | |
| SCHEMBL925941 | 0.71 | ALDH1A1 (0.53) | HSD17B10ACHEALDH1A1GLAMAPT | |
| SCHEMBL7364055 | 0.68 | RAB9A (0.48) | ALDH1A1MAPTPOLBGFERCACNA1B | |
| SCHEMBL22567 | 0.67 | ALDH1A1 (0.72) | HSD17B10ACHEALDH1A1TDP1RECQL | |
| SCHEMBL27909482 | 0.67 | ALDH1A1 (0.72) | HSD17B10ACHEALDH1A1TDP1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105408335-A | Pyrazolopyrrolidine derivatives and their use in the treatment of disease | NOVARTIS AG | 2016-03-16 | — | — | CN | disclosed |