Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP14 | P50281 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26136337 | 0.86 | MGLL (0.67) | MGLLSMN1; SMN2MMP2MMP9MMP14 | |
| SCHEMBL25227685 | 0.84 | MGLL (0.56) | MGLLSMN1; SMN2MMP2MMP9MMP14 | |
| SCHEMBL25222344 | 0.83 | RAB9A (0.58) | MGLLSMN1; SMN2MMP2MMP9MMP14 | |
| SCHEMBL1895641 | 0.82 | TAAR1 (0.58) | MGLLNPC1GAARAB9ATAAR1 | |
| SCHEMBL28680181 | 0.81 | MGLL (0.58) | MGLLSMN1; SMN2MMP2MMP9MMP14 | |
| SCHEMBL13799297 | 0.81 | MGLL (0.54) | MGLLSMN1; SMN2MMP2MMP9MMP14 | |
| SCHEMBL28052009 | 0.81 | L3MBTL1 (0.59) | MGLLGAA | |
| SCHEMBL11668425 | 0.80 | MGLL (0.77) | MGLL | |
| SCHEMBL28687007 | 0.80 | TRPV1 (0.53) | MGLLSMN1; SMN2MMP2MMP9MMP14 | |
| SCHEMBL28195245 | 0.80 | MGLL (0.52) | MGLLSMN1; SMN2MMP2MMP9MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102917590-B | Tricyclic compound and the PBK inhibitor containing described compound | ONCOTHERAPY SCIENCE, INC. (JP) | 2016-02-17 | — | — | CN | disclosed |