Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RBP4 | P02753 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.38 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4630905 | 0.88 | NOTUM (0.43) | NOTUMCTSSCFTRLMNAGAA | |
| SCHEMBL27273620 | 0.84 | CTSS (0.45) | NOTUMCTSSCFTRLMNAGAA | |
| SCHEMBL30935916 | 0.84 | LMNA (0.42) | NOTUMCTSSCFTRLMNAGAA | |
| SCHEMBL30935926 | 0.82 | CFTR (0.44) | NOTUMCTSSCFTRLMNAGAA | |
| SCHEMBL27867432 | 0.79 | LMNA (0.43) | CFTRLMNAALDH1A1TSHRKDM4E | |
| SCHEMBL22403860 | 0.77 | TAS2R14 (0.52) | NOTUMCFTRLMNAGAAPDK2 | |
| SCHEMBL30689795 | 0.77 | TAS2R14 (0.52) | NOTUMCFTRLMNAGAAPDK2 | |
| SCHEMBL45490 | 0.76 | LMNA (0.59) | NOTUMCFTRLMNAGAAPDK2 | |
| SCHEMBL5239843 | 0.75 | CTSS (0.51) | NOTUMCTSSCFTRLMNAGAA | |
| SCHEMBL726068 | 0.75 | TAS2R14 (0.54) | NOTUMCTSSCFTRLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103502242-B | Isoindoline ketone derivatives | HOFFMAN-LA ROCHE LTD. (CH) | 2016-01-20 | — | — | CN | disclosed |