Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | RORB | Q92753 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5849850 | 0.86 | BCAT2 (0.55) | KDM4EPOLBSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL31621277 | 0.86 | BCAT2 (0.55) | KDM4EPOLBSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL30892682 | 0.86 | BCAT2 (0.55) | KDM4EPOLBSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL8910680 | 0.83 | KDM4E (0.51) | KDM4EPOLBSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL28323302 | 0.81 | KDM4E (0.50) | KDM4EPOLBSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL9068297 | 0.81 | KEAP1 (0.56) | KDM4EPOLBSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL27830752 | 0.80 | NR4A1 (0.55) | KDM4EPOLBSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL30646218 | 0.78 | BCAT2 (0.63) | KDM4EPOLBSMN1; SMN2GAAALDH1A1 | |
| Carbamic Acid SCHEMBL31151006 | 0.78 | ALOX5 (0.54) | KDM4EGAAALDH1A1NR4A1NR4A2 | |
| SCHEMBL29381201 | 0.78 | KDM4E (0.68) | KDM4EPOLBSMN1; SMN2GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105294597-A | Benzothiazine derivative, and synthetic method and application thereof | UNIV EAST CHINA NORMAL | 2016-02-03 | — | — | CN | claimed |
| CN-105294597-B | Benzothiazine derivatives and its synthetic method and application | 华东师范大学 | 2017-11-24 | — | — | CN | disclosed |
| CN-105294597-A | Benzothiazine derivative, and synthetic method and application thereof | UNIV EAST CHINA NORMAL | 2016-02-03 | — | — | CN | disclosed |