Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31621277 | 0.87 | BCAT2 (0.55) | KDM4EALDH1A1GAAPOLBSMN1; SMN2 | |
| SCHEMBL30892682 | 0.87 | BCAT2 (0.55) | KDM4EALDH1A1GAAPOLBSMN1; SMN2 | |
| SCHEMBL5849850 | 0.87 | BCAT2 (0.55) | KDM4EALDH1A1GAAPOLBSMN1; SMN2 | |
| SCHEMBL18317957 | 0.85 | ALDH1A1 (0.56) | KDM4EALDH1A1GAABCAT2MAPT | |
| SCHEMBL2534284 | 0.84 | NR4A1 (0.63) | KDM4EALDH1A1POLBNR4A1NR4A2 | |
| SCHEMBL8910680 | 0.84 | KDM4E (0.51) | KDM4EALDH1A1GAAPOLBSMN1; SMN2 | |
| SCHEMBL9068297 | 0.82 | KEAP1 (0.56) | KDM4EALDH1A1GAAPOLBSMN1; SMN2 | |
| SCHEMBL28053358 | 0.81 | KDM4E (0.49) | KDM4EALDH1A1GAAPOLBSMN1; SMN2 | |
| SCHEMBL27830752 | 0.81 | NR4A1 (0.55) | KDM4EALDH1A1GAAPOLBSMN1; SMN2 | |
| SCHEMBL5049433 | 0.80 | KDM4E (0.61) | KDM4EALDH1A1GAASMN1; SMN2BCAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110352188-A | Fluoro allylamine derivatives and application thereof | 四川科伦博泰生物医药股份有限公司 | 2019-10-18 | — | — | CN | disclosed |