Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GOT1 | P17174 | 1/20 | 0.43 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.39 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | GPR6 | P46095 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | UBE2N | P61088 | 1/20 | 0.34 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.33 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.33 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL84649 | 0.82 | — | — | |
| Trifluoroacetic Acid SCHEMBL26645027 | 0.78 | CHIT1 (0.53) | CHIT1KMT2AKDM4EL3MBTL1 | |
| Isophthalic Acid SCHEMBL27861456 | 0.78 | SIRT2 (0.44) | GOT1KMT2ASIRT2HCAR3CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL30489000 | 0.74 | P2RX7 (0.49) | P2RX7KMT2ADPP4DPP8DPP9 | |
| Trifluoroacetic Acid SCHEMBL13736680 | 0.74 | P2RX7 (0.41) | GOT1P2RX7KMT2ADPP4DPP8 | |
| Trifluoroacetic Acid SCHEMBL25283802 | 0.71 | P2RX7 (0.50) | P2RX7KMT2ADPP4DPP8DPP9 | |
| SCHEMBL15348825 | 0.71 | GOT1 (0.52) | GOT1FFAR2P2RX7KMT2ASIRT2 | |
| SCHEMBL20606962 | 0.70 | FFAR2 (0.48) | GOT1FFAR2P2RX7SIRT2LCK | |
| Trifluoroacetic Acid SCHEMBL29116372 | 0.70 | HAO1 (0.37) | P2RX7KMT2ADPP4DPP8DPP9 | |
| Trifluoroacetic Acid SCHEMBL28546553 | 0.69 | KDM4E (0.42) | CHIT1KDM4EL3MBTL1UBE2N |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105452233-A | Piperidine and azepane derivatives as prokineticin receptor modulators | TAKEDA PHARMACEUTICALS CO | 2016-03-30 | — | — | CN | disclosed |