Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | MTOR | P42345 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30961455 | 1.00 | ATR (0.39) | ATRMLYCDPKMRAB9APIK3CA | |
| SCHEMBL29865799 | 0.81 | LMNA (0.54) | PKMRAB9ALMNASMN1; SMN2MEN1 | |
| SCHEMBL257468 | 0.81 | LMNA (0.54) | PKMRAB9ALMNASMN1; SMN2MEN1 | |
| SCHEMBL307136 | 0.78 | MLYCD (0.42) | MLYCDPKMRAB9ASLC6A3MEN1 | |
| SCHEMBL16523551 | 0.77 | ATR (0.36) | ATRLMNASMN1; SMN2KMT2APIK3C3 | |
| SCHEMBL8487096 | 0.77 | SLC6A3 (0.38) | ATRMLYCDPKMRAB9APIK3CA | |
| SCHEMBL1325584 | 0.76 | RAB9A (0.36) | ATRMLYCDPKMRAB9APIK3CA | |
| SCHEMBL1970174 | 0.76 | ATR (0.56) | ATRRAB9ASLC6A3LMNASMN1; SMN2 | |
| SCHEMBL31298634 | 0.75 | RAB9A (0.37) | ATRMLYCDPKMRAB9ASLC6A3 | |
| SCHEMBL568375 | 0.75 | RAB9A (0.37) | ATRMLYCDPKMRAB9ASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105283443-A | Heterocyclic derivatives and use thereof | C & C RES LAB | 2016-01-27 | — | — | CN | disclosed |