Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | HBB | P68871 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28053799 | 0.82 | GRM4 (0.56) | ALOX5MAPTNPC1SMN1; SMN2RAB9A | |
| SCHEMBL28053931 | 0.78 | NFE2L2 (0.55) | ALOX5MAPTNPC1RAB9AKDM4E | |
| SCHEMBL9000448 | 0.78 | MAPT (0.50) | ALOX5MAPTNPC1SMN1; SMN2RAB9A | |
| SCHEMBL9000449 | 0.78 | MAPT (0.50) | ALOX5MAPTNPC1SMN1; SMN2RAB9A | |
| SCHEMBL28053952 | 0.78 | CYP11B1 (0.56) | ALOX5MAPTNPC1RAB9AKDM4E | |
| SCHEMBL20144415 | 0.78 | BCHE (0.44) | TXNRD1TXNRD3TXNRD2BCHEACHE | |
| SCHEMBL28053932 | 0.76 | RELA (0.58) | ALOX5MAPTNPC1SMN1; SMN2RAB9A | |
| SCHEMBL107198 | 0.75 | MAPT (0.61) | ALOX5MAPTNPC1SMN1; SMN2RAB9A | |
| SCHEMBL138489 | 0.75 | MAPT (0.61) | ALOX5MAPTNPC1SMN1; SMN2RAB9A | |
| SCHEMBL9966009 | 0.72 | MAPT (0.65) | ALOX5MAPTNPC1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103864768-B | Ligustrazine stilbenoids derivatives and preparation method thereof and application | GUANGXI NORMAL UNIVERSITY (CN) | 2016-04-06 | — | — | CN | disclosed |