Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL304577 | 0.95 | L3MBTL1 (0.55) | L3MBTL1SMN1; SMN2TDP1ALDH1A1KEAP1 | |
| SCHEMBL304579 | 0.95 | L3MBTL1 (0.55) | L3MBTL1SMN1; SMN2TDP1ALDH1A1KEAP1 | |
| SCHEMBL304796 | 0.85 | L3MBTL1 (0.55) | L3MBTL1SMN1; SMN2TDP1ALDH1A1KEAP1 | |
| SCHEMBL26666242 | 0.84 | L3MBTL1 (0.49) | L3MBTL1SMN1; SMN2TDP1ALDH1A1KEAP1 | |
| SCHEMBL800478 | 0.84 | L3MBTL1 (0.49) | L3MBTL1SMN1; SMN2TDP1ALDH1A1KEAP1 | |
| SCHEMBL9860381 | 0.82 | KEAP1 (0.67) | SMN1; SMN2TDP1ALDH1A1KEAP1KMT2A | |
| SCHEMBL10193600 | 0.82 | KEAP1 (0.67) | SMN1; SMN2TDP1ALDH1A1KEAP1KMT2A | |
| SCHEMBL9860389 | 0.82 | KEAP1 (0.67) | SMN1; SMN2TDP1ALDH1A1KEAP1KMT2A | |
| Alcohol SCHEMBL28404120 | 0.82 | L3MBTL1 (0.52) | L3MBTL1SMN1; SMN2TDP1ALDH1A1KEAP1 | |
| SCHEMBL14390211 | 0.82 | ALDH1A1 (0.47) | L3MBTL1SMN1; SMN2TDP1ALDH1A1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102964239-B | metal-beta-lactamase inhibitor | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2016-01-20 | — | — | CN | disclosed |