Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL304579 | 0.89 | L3MBTL1 (0.55) | L3MBTL1SMN1; SMN2TDP1ALDH1A1ALOX5 | |
| SCHEMBL304577 | 0.89 | L3MBTL1 (0.55) | L3MBTL1SMN1; SMN2TDP1ALDH1A1ALOX5 | |
| SCHEMBL26666242 | 0.88 | L3MBTL1 (0.49) | L3MBTL1SMN1; SMN2TDP1ALDH1A1ALOX5 | |
| SCHEMBL28054355 | 0.84 | L3MBTL1 (0.51) | L3MBTL1SMN1; SMN2TDP1ALDH1A1ALOX5 | |
| SCHEMBL14390211 | 0.79 | ALDH1A1 (0.47) | L3MBTL1SMN1; SMN2TDP1ALDH1A1ALOX5 | |
| SCHEMBL304796 | 0.79 | L3MBTL1 (0.55) | L3MBTL1SMN1; SMN2TDP1ALDH1A1ALOX5 | |
| Alcohol SCHEMBL28404120 | 0.76 | L3MBTL1 (0.52) | L3MBTL1SMN1; SMN2TDP1ALDH1A1ALOX5 | |
| SCHEMBL8159651 | 0.76 | L3MBTL1 (0.52) | L3MBTL1SMN1; SMN2TDP1ALDH1A1ALOX5 | |
| SCHEMBL7299043 | 0.76 | MAPT (0.53) | L3MBTL1SMN1; SMN2TDP1ALDH1A1ALOX5 | |
| SCHEMBL16212254 | 0.76 | L3MBTL1 (0.52) | L3MBTL1SMN1; SMN2TDP1ALDH1A1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160151322-A1 | METALLO-B-LACTAMASE INHIBITORS | MEIJI SEIKA KAISHA (JP) | 2016-06-02 | — | — | US | disclosed |
| US-9260375-B2 | Metallo-β-lactamase inhibitors | MEIJI SEIKA KAISHA, LTD. (JP) | 2016-02-16 | — | — | US | disclosed |
| US-20120071457-A1 | METALLO-BETA-LACTAMASE INHIBITORS | CHIKAUCHI KEN (JP) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071457-A1 | METALLO-BETA-LACTAMASE INHIBITORS | ME1, MGAM, GAA | L3MBTL1 1177/4885SMN1; SMN2 2666/4885TDP1 2860/4885 |
| US-20160151322-A1 | METALLO-B-LACTAMASE INHIBITORS | ME1, MGAM, MANBA | L3MBTL1 933/4885SMN1; SMN2 2687/4885TDP1 3098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.