Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MERTK | Q12866 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TXNRD1 | Q16881 | 5/20 | 0.41 |
| ▸ | GSR | P00390 | 3/20 | 0.41 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.37 |
| ▸ | GLP1R | P43220 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSH | P09668 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31030224 | 0.81 | MERTK (0.48) | MAPTMERTKHTTTXNRD1GSR | |
| SCHEMBL2272996 | 0.77 | MAPT (0.48) | MAPTMERTKHTTTXNRD1GSR | |
| SCHEMBL18508375 | 0.74 | MEN1 (0.49) | MAPTMERTKHTTFGFR4TDP1 | |
| SCHEMBL18497220 | 0.73 | MEN1 (0.62) | MAPTMERTKHTTTXNRD1GSR | |
| SCHEMBL18508428 | 0.73 | MEN1 (0.51) | MAPTMERTKTXNRD1GSRFGFR4 | |
| SCHEMBL10699810 | 0.73 | ALDH1A1 (0.49) | MAPTMERTKHTTTXNRD1FGFR4 | |
| SCHEMBL28358902 | 0.72 | MEN1 (0.54) | MAPTHTTL3MBTL1TDP1POLB | |
| SCHEMBL28054769 | 0.72 | TXNRD1 (0.39) | TXNRD1GSRL3MBTL1ALDH1A1 | |
| SCHEMBL381701 | 0.72 | MERTK (0.51) | MAPTMERTKHTTTXNRD1GSR | |
| SCHEMBL29392605 | 0.72 | MERTK (0.51) | MAPTMERTKHTTTXNRD1GSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105254558-A | Dichloroallyl ether compound, preparation method and applications thereof | HUNAN CHEMICAL INDUSTRY INST CO LTD | 2016-01-20 | — | — | CN | disclosed |