Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7824587 | 0.83 | MEN1 (0.51) | MEN1KMT2ASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL4988971 | 0.81 | SMN1; SMN2 (0.61) | MEN1KMT2ASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL29627490 | 0.80 | MEN1 (0.61) | MEN1KMT2ASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL70297 | 0.80 | MEN1 (0.61) | MEN1KMT2ASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL6849222 | 0.80 | MEN1 (0.71) | MEN1KMT2ASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL17582469 | 0.78 | MEN1 (0.49) | MEN1KMT2ASMN1; SMN2GAAALDH1A1 | |
| Ethane SCHEMBL7553162 | 0.78 | MEN1 (0.55) | MEN1KMT2ASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL31676628 | 0.78 | SMN1; SMN2 (0.58) | MEN1KMT2ASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL13402273 | 0.78 | L3MBTL1 (0.58) | MEN1KMT2ASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL13596619 | 0.78 | SMN1; SMN2 (0.58) | MEN1KMT2ASMN1; SMN2GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110642838-B | EGFR inhibitor and preparation and application thereof | 江苏威凯尔医药科技有限公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-110642838-A | EGFR inhibitor and preparation and application thereof | 江苏威凯尔医药科技有限公司 | 2020-01-03 | — | — | CN | disclosed |