Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | PAM | P19021 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CTRC | Q99895 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | GNPAT | O15228 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7796543 | 1.00 | CTRB1 (0.59) | CTRB1LMNACTSSCTSKPAM | |
| SCHEMBL7626858 | 0.86 | CTRB1 (0.50) | CTRB1NPC1RAB9ATAAR1ALPI | |
| SCHEMBL3554246 | 0.86 | CTRB1 (0.50) | CTRB1NPC1RAB9ATAAR1ALPI | |
| SCHEMBL5563236 | 0.85 | CAPN1 (0.58) | CTRB1 | |
| SCHEMBL2269431 | 0.85 | CAPN1 (0.58) | CTRB1 | |
| SCHEMBL2266848 | 0.85 | CAPN1 (0.58) | CTRB1 | |
| SCHEMBL7796647 | 0.84 | CTSK (0.47) | CTRB1CTSKNPC1RAB9ATAAR1 | |
| SCHEMBL7797929 | 0.84 | CTSB (0.50) | CTRB1NPC1RAB9ATAAR1 | |
| SCHEMBL7796596 | 0.84 | NPC1 (0.46) | CTRB1CTSKNPC1RAB9ATAAR1 | |
| SCHEMBL6444348 | 0.83 | CPA1 (0.44) | CTRB1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105348224-A | Preparation method for amprenavir intermediate | SHANGHAI INST TECHNOLOGY | 2016-02-24 | — | — | CN | claimed |
| CN-105348224-A | Preparation method for amprenavir intermediate | SHANGHAI INST TECHNOLOGY | 2016-02-24 | — | — | CN | disclosed |