Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | CTRB1 | P17538 | 4/20 | 0.45 |
| ▸ | CTSB | P07858 | 3/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSH | P09668 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7796605 | 0.86 | PSMB8 (0.56) | PSMB5CTSBCTSL | |
| SCHEMBL16153848 | 0.86 | CTSB (0.57) | CTSBCAPN1CTSLCTSHCTSK | |
| SCHEMBL7796543 | 0.84 | CTRB1 (0.59) | NPC1RAB9ACTRB1TAAR1CTSK | |
| SCHEMBL28055494 | 0.84 | CTRB1 (0.59) | NPC1RAB9ACTRB1TAAR1CTSK | |
| SCHEMBL3554246 | 0.83 | CTRB1 (0.50) | NPC1RAB9APSMB5CTRB1TAAR1 | |
| SCHEMBL7626858 | 0.83 | CTRB1 (0.50) | NPC1RAB9APSMB5CTRB1TAAR1 | |
| SCHEMBL7797929 | 0.81 | CTSB (0.50) | NPC1RAB9ACTRB1CTSBTAAR1 | |
| SCHEMBL7796647 | 0.81 | CTSK (0.47) | NPC1RAB9ACTRB1CTSBTAAR1 | |
| SCHEMBL7800081 | 0.81 | MMP8 (0.49) | CTRB1CTSBCTSLCTSHCTSK | |
| SCHEMBL7799013 | 0.80 | CTSB (0.46) | NPC1RAB9ACTRB1CTSBTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748801-B1 | 2-ISOXAZOLINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME, AND PROCESS FOR PRODUCING RELATED DERIVATIVES FROM THE SAME | DAICEL CHEM (JP) | 2001-12-19 | — | — | EP | disclosed |
| US-6018069-A | 2-isoxazoline derivative and process for producing the same and process for producing related derivatives from the same | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2000-01-25 | — | — | US | disclosed |
| US-5994558-A | 2-isoxazoline derivative and process for producing the same; and process for producing related derivatives from the same | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-30 | — | — | US | disclosed |
| US-5962692-A | 2-isoxazoline derivative and process for producing the same, and process for producing related derivatives from the same | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5750717-A | 2-isoxazoline derivative and process for producing the same, and process for producing related derivatives from the same | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0748801-A1 | 2-ISOXAZOLINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME, AND PROCESS FOR PRODUCING RELATED DERIVATIVES FROM THE SAME | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-18 | — | — | EP | disclosed |