SCHEMBL4640466

SCHEMBL4640466

FC(F)(F)c1ccc2ocnc2c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 1/20 0.45
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44
ALDH1A1 P00352 1/20 0.44
GAA P10253 1/20 0.44
KMT2A Q03164 1/20 0.44
PARP1 P09874 1/20 0.40
CTNNB1 P35222 3/20 0.40
WNT3A P56704 3/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
PKM P14618 1/20 0.39
EPHX2 P34913 2/20 0.38
NOS3 P29474 1/20 0.37
NOS2 P35228 1/20 0.37
BACE1 P56817 1/20 0.37
CHRNB2 P17787 1/20 0.37
CHRNA4 P43681 1/20 0.37
NOTUM Q6P988 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31391349 1.00 DYRK1A (0.45) DYRK1AKDM4EMEN1ALDH1A1GAA
SCHEMBL28056267 0.85 KDM4E (0.49) DYRK1AKDM4EPARP1NPC1RAB9A
SCHEMBL18463899 0.81 DYRK1A (0.42) DYRK1AMEN1ALDH1A1GAAKMT2A
SCHEMBL2079591 0.81 DYRK1A (0.45) DYRK1AMEN1ALDH1A1GAAKMT2A
SCHEMBL11683134 0.81 DYRK1A (0.45) DYRK1AMEN1ALDH1A1GAAKMT2A
SCHEMBL29384003 0.81 DYRK1A (0.45) DYRK1AMEN1ALDH1A1GAAKMT2A
SCHEMBL15979956 0.76 CTNNB1 (0.71) MEN1ALDH1A1GAAKMT2ACTNNB1
SCHEMBL10263739 0.75 MEN1 (0.43) DYRK1AMEN1ALDH1A1GAAKMT2A
SCHEMBL21191750 0.75 MEN1 (0.43) DYRK1AMEN1ALDH1A1GAAKMT2A
SCHEMBL29770908 0.75 MEN1 (0.43) DYRK1AMEN1ALDH1A1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 233 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0278509-B1 Silver halide photographic emulsion FUJI PHOTO FILM CO LTD (JP) 1996-01-24 EP claimed
US-4970141-A ELEVATED SPECTRAL SENSITIVITY IN GREEN WAVELENGTH REGION FUJI PHOTO FILM CO., LTD. (JP) 1990-11-13 US claimed
US-4889796-A CONTAINING BENZOXAZOLE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1989-12-26 US claimed
EP-0278509-A2 Silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. (JP) 1988-08-17 EP claimed
US-4154616-A BENZOXAZOLE OR NAPHTHOXAZOLE MEROCYANINE DYE FUJI PHOTO FILM CO., LTD. (JP) 1979-05-15 US claimed
US-4102688-A CONTAINING PYRAZOLO(3,4-B)PYRIDINE/3,6-DIONE MOIETY FUJI PHOTO FILM CO., LTD. (JP) 1978-07-25 US claimed
US-4057430-A MEROCYANINE THIOHYDANTOIN SENSITIZERS FUJI PHOTO FILM CO., LTD. (JA) 1977-11-08 US claimed
US-3977882-A CARBOCYANINE DYES FUJI PHOTO FILM CO., LTD. (JA) 1976-08-31 US claimed
US-20250171437-A1 (4-BENZO[D]OXAZOL-2-YL)-6,7-DIHYDRO-1H-IMIDAZO[4,5-C]PYRIDINE-5(4H)-YL)METHANONE DERIVATIVES AS MUTANT PAH STABILIZERS FOR THE TREATMENT OF PHENYLKETONURIA AGIOS PHARMACEUTICALS, INC. 2025-05-29 US disclosed
US-20230167122-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS SYNGENTA CROP PROTECTION AG (CH) 2023-06-01 US disclosed
EP-3145925-B1 ANTHELMINTIC COMPOUNDS BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) 2020-11-04 EP disclosed
US-10463661-B2 Anthelmintic compounds Boehringer Ingelheim Animal Health USA Inc. (US) 2019-11-05 US disclosed
US-20190194179-A1 ANTIBIOTIC COMPOUNDS DISCUVA LTD. (GB) 2019-06-27 US disclosed
US-20190194179-A1 ANTIBIOTIC COMPOUNDS DISCUVA LTD. (GB) 2019-06-27 US disclosed
US-3977882-A CARBOCYANINE DYES FUJI PHOTO FILM CO., LTD. (JA) 1976-08-31 US disclosed
US-3977883-A Spectrally sensitized silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. (JA) 1976-08-31 US disclosed
US-3967967-A CYANINE DYES FUJI PHOTO FILM CO., LTD. (JA) 1976-07-06 US disclosed
US-3966477-A Spectrally sensitized silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. (JA) 1976-06-29 US disclosed
US-3953216-A BENZOXAZOLES, NAPHTHOXAZOLES FUJI PHOTO FILM CO., LTD. (JA) 1976-04-27 US disclosed
US-3953215-A X-RAY FILM FUJI PHOTO FILM CO., LTD. (JA) 1976-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250171437-A1 (4-BENZO[D]OXAZOL-2-YL)-6,7-DIHYDRO-1H-IMIDAZO[4,5-C]PYRIDINE-5(4H)-YL)METHANONE DERIVATIVES AS MUTANT PAH STABILIZERS FOR THE TREATMENT OF PHENYLKETONURIA PAH, BCKDK, PKM DYRK1A 1030/4885KDM4E 50/4885MEN1 3681/4885
US-10463661-B2 Anthelmintic compounds HRH4, QTRT1, Q6ZSR9 DYRK1A 2252/4885KDM4E 426/4885MEN1 3775/4885
US-20190194179-A1 ANTIBIOTIC COMPOUNDS B3GNT2, RPN2, RPN1 DYRK1A 4530/4885KDM4E 3731/4885MEN1 725/4885
US-20230167122-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS DDT, AADAC, ACAA2 DYRK1A 3169/4885KDM4E 1923/4885MEN1 2325/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.