Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28056953 | 0.81 | KDM4E (0.36) | KDM4ETP53ALDH1A1MGLLTERT | |
| SCHEMBL28056959 | 0.80 | KDM4E (0.41) | KDM4ECHRM2CHRM1ALDH1A1MGLL | |
| SCHEMBL28056958 | 0.77 | MGLL (0.41) | KDM4ECHRM2CHRM1CHRM3ALDH1A1 | |
| SCHEMBL28056873 | 0.72 | MAPT (0.52) | CHRM2CHRM1CHRM3MAPTLMNA | |
| SCHEMBL28056866 | 0.71 | SLC6A9 (0.43) | ALDH1A1HPGDTERT | |
| SCHEMBL7164239 | 0.70 | IDO1 (0.49) | KDM4EIDO1ALDH1A1MAPTTERT | |
| SCHEMBL31319077 | 0.70 | TP53 (0.43) | KDM4EIDO1TP53ALDH1A1MAPT | |
| SCHEMBL21807618 | 0.69 | PKM (0.44) | KDM4EIDO1ALDH1A1MAPTTERT | |
| Ethylene SCHEMBL28056955 | 0.68 | LMNA (0.38) | KDM4EALDH1A1MAPTHPGDLMNA | |
| SCHEMBL7628635 | 0.68 | IDO1 (0.46) | KDM4EIDO1ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103992265-B | Two three bromo 1,3-bis-pyridine alkali propane and preparation method thereof, using method, recovery method and application | XI'AN JIAOTONG UNIVERSITY (CN) | 2016-02-24 | — | — | CN | disclosed |