Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSPO | P30536 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28056867 | 0.81 | KDM4E (0.36) | KDM4ETP53ALDH1A1MGLLTERT | |
| SCHEMBL28056866 | 0.76 | SLC6A9 (0.43) | ALDH1A1TERTDRD3POLB | |
| SCHEMBL28056958 | 0.74 | MGLL (0.41) | KDM4EALDH1A1MGLLDRD3 | |
| SCHEMBL28056873 | 0.74 | MAPT (0.52) | HTTMEN1KMT2ALMNA | |
| SCHEMBL27977315 | 0.71 | DRD3 (0.39) | KDM4ETP53ALDH1A1HTTMEN1 | |
| SCHEMBL28056956 | 0.69 | MAPT (0.41) | KDM4EALDH1A1MGLLMEN1KMT2A | |
| SCHEMBL28056871 | 0.69 | EPHX1 (0.35) | KDM4EALDH1A1KMT2ALMNA | |
| SCHEMBL28826651 | 0.68 | ABAT (0.35) | KDM4EALDH1A1MGLLHRH3 | |
| SCHEMBL28056959 | 0.68 | KDM4E (0.41) | KDM4EALDH1A1MGLLDRD3LMNA | |
| SCHEMBL28056872 | 0.67 | ALDH1A1 (0.42) | KDM4EALDH1A1HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103992265-B | Two three bromo 1,3-bis-pyridine alkali propane and preparation method thereof, using method, recovery method and application | XI'AN JIAOTONG UNIVERSITY (CN) | 2016-02-24 | — | — | CN | disclosed |