Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 10/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | BTK | Q06187 | 3/20 | 0.42 |
| ▸ | JAK2 | O60674 | 2/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27982181 | 0.89 | ALDH1A1 (0.49) | PARP1KDM4EALDH1A1BTKJAK2 | |
| SCHEMBL28058608 | 0.84 | KDM4E (0.45) | PARP1KDM4EALDH1A1BTKJAK2 | |
| SCHEMBL15995219 | 0.81 | HTR7 (0.46) | PARP1KDM4EALDH1A1BTKJAK2 | |
| SCHEMBL152790 | 0.81 | BTK (0.41) | PARP1KDM4EALDH1A1BTKJAK2 | |
| SCHEMBL30849286 | 0.80 | KIF11 (0.50) | PARP1KDM4EALDH1A1BTKJAK2 | |
| SCHEMBL6129592 | 0.79 | IMPDH2 (0.55) | PARP1KDM4EALDH1A1DYRK1A | |
| SCHEMBL30006934 | 0.79 | IMPDH2 (0.55) | PARP1KDM4EALDH1A1DYRK1A | |
| SCHEMBL3690163 | 0.77 | KIF11 (0.41) | PARP1KDM4EALDH1A1KIF11MAOA | |
| SCHEMBL15995032 | 0.76 | BTK (0.46) | PARP1BTKJAK2KIF11 | |
| SCHEMBL149527 | 0.75 | BTK (0.47) | PARP1KDM4EALDH1A1BTKJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105473573-A | Carbazole carboxamide compounds useful as kinase inhibitors | BRISTOL MYERS SQUIBB CO | 2016-04-06 | — | — | CN | disclosed |