Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.50 |
| ▸ | PARP1 | P09874 | 5/20 | 0.46 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | CCND1 | P24385 | 1/20 | 0.44 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.44 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.44 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.44 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.42 |
| ▸ | GABRE | P78334 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15995219 | 0.84 | HTR7 (0.46) | KIF11PARP1JAK2KDM4EALDH1A1 | |
| SCHEMBL6129592 | 0.81 | IMPDH2 (0.55) | PARP1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL30006934 | 0.81 | IMPDH2 (0.55) | PARP1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL15995032 | 0.81 | BTK (0.46) | KIF11PARP1JAK2BTK | |
| SCHEMBL28058638 | 0.80 | PARP1 (0.49) | KIF11PARP1CDK4CCND1JAK2 | |
| SCHEMBL27982181 | 0.80 | ALDH1A1 (0.49) | KIF11PARP1CDK4CCND1JAK2 | |
| SCHEMBL15994776 | 0.80 | BTK (0.50) | KIF11PARP1JAK2BTK | |
| SCHEMBL28058608 | 0.79 | KDM4E (0.45) | KIF11PARP1JAK2KDM4EALDH1A1 | |
| SCHEMBL15994772 | 0.77 | PARP1 (0.46) | PARP1JAK2ALDH1A1BTK | |
| SCHEMBL22514642 | 0.76 | KIF11 (0.61) | KIF11PARP1CDK4CCND1CAMK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3448378-B1 | PLA2 AND HMG-COA INHIBITORS FOR TREATMENT OF PATHOLOGICAL CONDITIONS CAUSING HEMOLYSIS, CEREBRAL EDEMA, AND ACUTE KIDNEY INJURY | OPHIREX INC (US) | 2024-04-17 | — | — | EP | disclosed |