SCHEMBL28058776

SCHEMBL28058776

CC(N)CCCC(Oc1ccccc1)C(N)=O

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PPARG P37231 11/20 0.42
PPARA Q07869 10/20 0.42
MTNR1A P48039 1/20 0.41
MTNR1B P49286 1/20 0.41
TDP1 Q9NUW8 1/20 0.39
ALOX5 P09917 2/20 0.39
POLB P06746 1/20 0.39
FOLH1 Q04609 1/20 0.39
CTRC Q99895 1/20 0.39
GAA P10253 1/20 0.38
PTGES O14684 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4788224 0.91 PPARG (0.48) PPARGPPARAFOLH1
SCHEMBL14159647 0.83 CTRC (0.53) PPARGPPARAALOX5CTRCPTGES
Hydrochloric Acid SCHEMBL30415831 0.80 PPARG (0.55) PPARGPPARAMTNR1AMTNR1BCTRC
SCHEMBL7890153 0.79 PPARG (0.45) PPARGPPARA
SCHEMBL10652176 0.79 PPARG (0.52) PPARGPPARATDP1ALOX5CTRC
SCHEMBL11664164 0.78 CTSK (0.50) PPARGPPARAMTNR1AMTNR1BPOLB
SCHEMBL1433697 0.77 ALDH1A1 (0.52) PPARGPPARAPOLB
SCHEMBL5671174 0.73 ALDH1A1 (0.47) PPARGPPARATDP1
SCHEMBL11019359 0.72 PPARG (0.62) PPARGPPARAMTNR1AMTNR1B
SCHEMBL5272171 0.72 PPARG (0.66) PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105439914-A 4-aminoacylphenoxyacetamide compound and medicine uses thereof UNIV FUDAN 2016-03-30 CN disclosed
CN-105439914-A 4-aminoacylphenoxyacetamide compound and medicine uses thereof UNIV FUDAN 2016-03-30 CN disclosed