Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 7/20 | 0.49 |
| ▸ | ESR1 | P03372 | 4/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1861170 | 0.85 | ADORA2A (0.54) | ERN1KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL28058893 | 0.74 | CSNK2A2 (0.58) | ESR1ESR2KDM4EALDH1A1MAPT | |
| SCHEMBL3262155 | 0.72 | NPSR1 (0.45) | ERN1ESR1ESR2KDM4EMEN1 | |
| SCHEMBL5867251 | 0.71 | GPR35 (0.55) | ERN1KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL1861098 | 0.71 | HSD17B3 (0.60) | ESR2KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL28066198 | 0.68 | TYR (0.51) | ERN1ESR1ESR2HPGDADORA3 | |
| SCHEMBL31300223 | 0.68 | ERN1 (0.54) | ERN1KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL219677 | 0.68 | ERN1 (0.54) | ERN1KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL11585942 | 0.67 | ALDH1A1 (0.57) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL6828285 | 0.67 | ESR2 (0.68) | ESR1ESR2CSNK2A2CSNK2BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029017-A1 | Mono-chlorinated hydroxycoumarin conjugates | BECTON, DICKINSON AND COMPANY | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029017-A1 | Mono-chlorinated hydroxycoumarin conjugates | CLSPN, CLTC, HACD3 | ERN1 4838/4885ESR1 3963/4885ESR2 4317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.