SCHEMBL28060058

SCHEMBL28060058

[c]1ccc(C=Cc2ccc(C34CC5CC(CC(C5)C3)C4)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.50
ALDH1A1 P00352 3/20 0.50
GAA P10253 2/20 0.44
EPHX2 P34913 6/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
POLB P06746 1/20 0.42
GFER P55789 1/20 0.42
NPC1 O15118 1/20 0.41
RARB P10826 2/20 0.40
RARA P10276 1/20 0.40
RARG P13631 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
MAPT P10636 1/20 0.39
RAB9A P51151 1/20 0.38
GRIN2D O15399 1/20 0.37
GRIN3B O60391 1/20 0.37
GRIN1 Q05586 1/20 0.37
GRIN2A Q12879 1/20 0.37
GRIN2B Q13224 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL67257 0.83 LMNA (0.57) LMNAALDH1A1GAAEPHX2MEN1
SCHEMBL18317467 0.80 LMNA (0.55) LMNAALDH1A1GAAEPHX2MEN1
SCHEMBL28803691 0.79 LMNA (0.50) LMNAALDH1A1GAAEPHX2MEN1
SCHEMBL13636765 0.79 LMNA (0.50) LMNAALDH1A1GAAEPHX2MEN1
SCHEMBL2763437 0.77 LMNA (0.77) LMNAALDH1A1GAAEPHX2MEN1
SCHEMBL21220794 0.75 LMNA (0.45) LMNAALDH1A1GAAEPHX2MEN1
SCHEMBL10012164 0.74 ALDH1A1 (0.57) LMNAALDH1A1GAAEPHX2MEN1
SCHEMBL2776531 0.74 ALDH1A1 (0.57) LMNAALDH1A1GAAEPHX2MEN1
SCHEMBL548601 0.74 ALDH1A1 (0.57) LMNAALDH1A1GAAEPHX2MEN1
SCHEMBL677047 0.74 ALDH1A1 (0.57) LMNAALDH1A1GAAEPHX2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105601813-B A kind of modified polyvinyl carbazoles high-molecular luminous material and preparation method thereof 广东工业大学 2017-12-22 CN disclosed
CN-105601813-A Modified polyvinyl carbazole high-polymer luminescent material and preparation method thereof UNIV GUANGDONG TECHNOLOGY 2016-05-25 CN disclosed