Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21220794 | 0.91 | LMNA (0.45) | LMNAALDH1A1EPHX2MEN1KMT2A | |
| SCHEMBL18317467 | 0.88 | LMNA (0.55) | LMNAALDH1A1EPHX2MEN1KMT2A | |
| SCHEMBL28060058 | 0.83 | LMNA (0.50) | LMNAALDH1A1EPHX2MEN1KMT2A | |
| SCHEMBL2763437 | 0.83 | LMNA (0.77) | LMNAALDH1A1EPHX2MEN1KMT2A | |
| SCHEMBL548018 | 0.80 | ALDH1A1 (0.36) | LMNAALDH1A1EPHX2GRIN2DGRIN3B | |
| SCHEMBL996302 | 0.79 | GRIN2D (0.44) | LMNAALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL19813742 | 0.77 | LMNA (0.47) | LMNAALDH1A1EPHX2MEN1KMT2A | |
| SCHEMBL6637675 | 0.77 | ALDH1A1 (0.47) | LMNAALDH1A1EPHX2MEN1KMT2A | |
| SCHEMBL18317663 | 0.77 | MEN1 (0.44) | LMNAALDH1A1EPHX2MEN1KMT2A | |
| SCHEMBL181479 | 0.76 | GRIN2D (0.62) | LMNAALDH1A1EPHX2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 946 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116535329-A | Synthetic method of NOBIN-type axial chiral biaryl compound and compound thereof | 湖南师范大学 | 2023-08-04 | — | — | CN | claimed |
| CN-115811921-A | Organic electroluminescent device | 长春海谱润斯科技股份有限公司 | 2023-03-17 | — | — | CN | claimed |
| EP-2915824-B1 | METALLOCENE LIGANDS, METALLOCENE COMPOUNDS AND METALLOCENE CATALYSTS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS | LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) | 2022-05-25 | — | — | EP | claimed |
| EP-2915824-A1 | METALLOCENE LIGANDS, METALLOCENE COMPOUNDS AND METALLOCENE CATALYSTS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS | Lummus Novolen Technology Gmbh (DE) | 2015-09-09 | — | — | EP | claimed |
| EP-2456435-B1 | HETEROARYL BENZAMIDES, COMPOSITIONS AND METHODS OF USE | UNIV LELAND STANFORD JUNIOR (US) | 2015-06-24 | — | — | EP | claimed |
| EP-1548023-B1 | Transition metal compound, catalyst system and the use of the latter for the polymerisation and copolymerisation of olefins | BASELL POLYOLEFINE GMBH (DE) | 2013-08-14 | — | — | EP | claimed |
| US-8415492-B2 | Metallocene compounds, catalysts comprising them, process for producing an olefin polymer by use of the catalysts, and olefin homo- and copolymers | LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) | 2013-04-09 | — | — | US | claimed |
| US-20120329964-A1 | METALLOCENE COMPOUNDS, CATALYSTS COMPRISING THEM, PROCESS FOR PRODUCING AN OLEFIN POLYMER BY USE OF THE CATALYSTS, AND OLEFIN HOMO- AND COPOLYMERS | LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) | 2012-12-27 | — | — | US | claimed |
| US-20120225862-A1 | HETEROARYL BENZAMIDES, COMPOSITIONS AND METHODS OF USE | AUCKLAND UNIVSERVICES LIMITED (NZ) | 2012-09-06 | — | — | US | claimed |
| EP-2456435-A1 | HETEROARYL BENZAMIDES, COMPOSITIONS AND METHODS OF USE | The Board of Trustees of The Leland Stanford Junior University (US) | 2012-05-30 | — | — | EP | claimed |
| US-6444606-B1 | CATALYST SYSTEM COMPRISING AT LEAST ONE METALLOCENE COMPONENT, AT LEAST ONE COCATALYST AND AT LEAST ONE SUPPORT | BASELL POLYPROPYLEN GMBH (DE) | 2002-09-03 | — | — | US | claimed |
| US-6432993-B1 | BENZIMIDAZOLE OR IMIDAZO(4,5-B)PYRIDINE DERIVATES; IMMUNOMODULATORS; ALDOSE REDUCTASE AND LIPOXYGENASE INHIBITORS; DIABETES; PREVENTS LIPID PEROXIDATION; ANTILIPEMIC, HYPOTENSIVE AGENTS | SANKYO COMPANY, LIMITED (JP) | 2002-08-13 | — | — | US | claimed |
| WO-2001048034-A2 | TRANSITION METAL COMPOUND, LIGAND SYSTEM, CATALYST SYSTEM AND THE USE OF THE LATTER FOR THE POLYMERISATION AND COPOLYMERISATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2001-07-05 | — | — | WO | claimed |
| EP-1082363-A1 | ORGANOMETAL COMPOUND, CATALYST SYSTEM CONTAINING SAID ORGANOMETAL COMPOUND AND ITS USE | Basell Polyolefine GmbH (DE) | 2001-03-14 | — | — | EP | claimed |
| CN-1280570-A | Substituted fused heterocyclic compounds | SANKYO CO (JP) | 2001-01-17 | — | — | CN | claimed |
| WO-2000044799-A1 | ORGANOMETAL COMPOUND, CATALYST SYSTEM CONTAINING SAID ORGANOMETAL COMPOUND AND ITS USE | TARGOR GMBH (DE) | 2000-08-03 | — | — | WO | claimed |
| EP-1022272-A1 | SUBSTITUTED FUSED HETEROCYCLIC COMPOUNDS | Sankyo Company Limited (JP) | 2000-07-26 | — | — | EP | claimed |
| EP-0942938-A1 | SUPPORTED CATALYST SYSTEM, METHOD FOR THE PRODUCTION AND USE THEREOF IN OLEFIN POLYMERIZATION | Basell Polyolefine GmbH (DE) | 1999-09-22 | — | — | EP | claimed |
| WO-1998040416-A1 | SUPPORTED CATALYST SYSTEM, METHOD FOR THE PRODUCTION AND USE THEREOF IN OLEFIN POLYMERIZATION | TARGOR GMBH (DE) | 1998-09-17 | — | — | WO | claimed |
| US-4691051-A | Adamantyl phenyl β-alanines | PENNWALT CORPORATION (US) | 1987-09-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120329964-A1 | METALLOCENE COMPOUNDS, CATALYSTS COMPRISING THEM, PROCESS FOR PRODUCING AN OLEFIN POLYMER BY USE OF THE CATALYSTS, AND OLEFIN HOMO- AND COPOLYMERS | PIN1, PCNA, OPRM1 | LMNA 3102/4885ALDH1A1 3312/4885EPHX2 1548/4885 |
| US-20120225862-A1 | HETEROARYL BENZAMIDES, COMPOSITIONS AND METHODS OF USE | BRDT, NISCH, PAICS | LMNA 575/4885ALDH1A1 1336/4885EPHX2 326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.