Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27968794 | 0.82 | PTPN2 (0.37) | GAAALDH1A1RAB9ANPC1KMT2A | |
| SCHEMBL16992001 | 0.80 | MAPK1 (0.49) | MAPK1GAAALDH1A1RAB9ANPC1 | |
| SCHEMBL27987722 | 0.80 | L3MBTL1 (0.39) | MAPK1ALDH1A1RAB9ANPC1EPHX2 | |
| SCHEMBL28060472 | 0.79 | HTT (0.45) | MAPK1GAAALDH1A1EPHX2LMNA | |
| SCHEMBL28060475 | 0.79 | CTSK (0.42) | GAAALDH1A1EPHX2LMNACYP2C9 | |
| SCHEMBL1437590 | 0.78 | EPHX2 (0.49) | MAPK1GAAALDH1A1EPHX2L3MBTL1 | |
| SCHEMBL28064466 | 0.78 | SMN1; SMN2 (0.54) | GAAALDH1A1RAB9ANPC1MEN1 | |
| SCHEMBL27643661 | 0.78 | HPGD (0.36) | ALDH1A1MEN1KMT2ALMNATSHR | |
| SCHEMBL27566300 | 0.78 | HPGD (0.36) | ALDH1A1MEN1KMT2ALMNATSHR | |
| SCHEMBL1514783 | 0.77 | EPHX1 (0.64) | MAPK1ALDH1A1RAB9ANPC1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851610-A | Azabicyclo compound as muscarine M1 and/or M4 receptor stimulating agent | 赫普泰雅治疗有限公司 | 2019-06-07 | — | — | CN | disclosed |
| CN-106458986-B | Bicyclic aza compounds as muscarinic M1 and/or M4 receptor agonists | 赫普泰雅治疗有限公司 | 2019-01-04 | — | — | CN | disclosed |
| CN-106458986-A | Bicyclic aza compounds as muscarinic M1 and/or M4 receptor agonists | 赫普泰雅治疗有限公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-105399698-A | Aromatic heterocyclic derivatives and applications of aromatic heterocyclic derivatives in medicines | GUANGDONG HEC PHARMACEUTICAL | 2016-03-16 | — | — | CN | disclosed |