SCHEMBL544710

SCHEMBL544710

C=C(C)COc1ccc(O)c(-n2nc3ccccc3n2)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 8/20 0.54
NPC1 O15118 2/20 0.54
RAB9A P51151 2/20 0.54
MEN1 O00255 12/20 0.45
KMT2A Q03164 12/20 0.45
MAPT P10636 12/20 0.45
NPSR1 Q6W5P4 10/20 0.45
ALOX12 P18054 5/20 0.45
TP53 P04637 7/20 0.44
MAPK1 P28482 7/20 0.44
KDM4E B2RXH2 6/20 0.44
USP2 O75604 5/20 0.44
HSD17B10 Q99714 4/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
POLB P06746 3/20 0.44
ALOX15 P16050 2/20 0.44
ALDH1A1 P00352 6/20 0.42
HPGD P15428 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
GAA P10253 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2729117 0.90 KMT2A (0.47) LMNANPC1RAB9AMEN1KMT2A
SCHEMBL2806065 0.83 NPC1 (0.59) LMNANPC1RAB9AMEN1KMT2A
SCHEMBL9061067 0.82 NPC1 (0.50) LMNANPC1RAB9AMEN1KMT2A
SCHEMBL29768249 0.81 NPC1 (0.56) LMNANPC1RAB9AMEN1KMT2A
SCHEMBL10620345 0.81 LMNA (0.56) LMNANPC1RAB9AKMT2AMAPT
SCHEMBL9408814 0.81 NPC1 (0.56) LMNANPC1RAB9AMEN1KMT2A
SCHEMBL4185113 0.80 NPC1 (0.46) LMNANPC1RAB9AMAPTNPSR1
SCHEMBL11135110 0.80 NPC1 (0.54) LMNANPC1RAB9AMAPTMAPK1
SCHEMBL4188814 0.79 TDP1 (0.46) LMNANPC1RAB9AMAPTNPSR1
SCHEMBL29315604 0.79 TDP1 (0.48) LMNANPC1RAB9AMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025132506-A1 TOPICAL VETERINARY PRODUCTS AND RELATED METHODS INTERVET INTERNATIONAL B.V. (NL) 2025-06-26 WO disclosed
EP-2799455-B1 Resin composition for optical member and optical member obtained from the same MITSUBISHI GAS CHEMICAL CO (JP) 2018-03-28 EP disclosed
EP-2463318-B1 Resin composition for optical member and optical member obtained from the same MITSUBISHI GAS CHEMICAL CO (JP) 2015-01-14 EP disclosed
EP-2799455-A2 Resin composition for optical member and optical member obtained from the same MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2014-11-05 EP disclosed
EP-2128178-B1 RESIN COMPOSITION FOR OPTICAL MEMBER AND OPTICAL MEMBER OBTAINED FROM THE SAME MITSUBISHI GAS CHEMICAL CO (JP) 2013-04-24 EP disclosed
US-8389671-B2 Resin composition for optical member and optical member obtained from the same MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2013-03-05 US disclosed
EP-2463318-A1 Resin composition for optical member and optical member obtained from the same Mitsubishi Gas Chemical Company, Inc. (JP) 2012-06-13 EP disclosed
US-8110589-B2 Ectoparasiticide composition and a method for exterminating extoparasites KYOYU AGRI CO., LTD. (JP) 2012-02-07 US disclosed
US-20100130661-A1 RESIN COMPOSITION FOR OPTICAL MEMBER AND OPTICAL MEMBER OBTAINED FROM THE SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2010-05-27 US disclosed
US-20090312378-A1 ECTOPARASITICIDE COMPOSITION AND A METHOD FOR EXTERMINATING ECTOPARASITES YASHIMA SANGYO CO., LTD. (JP) 2009-12-17 US disclosed
EP-2128178-A1 RESIN COMPOSITION FOR OPTICAL MEMBER AND OPTICAL MEMBER OBTAINED FROM THE SAME Mitsubishi Gas Chemical Company, Inc. (JP) 2009-12-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090312378-A1 ECTOPARASITICIDE COMPOSITION AND A METHOD FOR EXTERMINATING ECTOPARASITES EPX, TYR, PPOX LMNA 3492/4885NPC1 4771/4885RAB9A 3780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.