Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 4/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CPA3 | P15088 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.31 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.30 |
| ▸ | ACP3 | P15309 | 1/20 | 0.30 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18085416 | 0.81 | EPHX1 (0.48) | EPHX1CTSKTAAR1CYP1A2MEN1 | |
| SCHEMBL27998281 | 0.80 | — | — | |
| SCHEMBL28074772 | 0.79 | CTSK (0.36) | EPHX1CTSKTAAR1CYP1A2MEN1 | |
| SCHEMBL28045730 | 0.78 | CTSK (0.37) | EPHX1CTSKTAAR1CYP1A2MEN1 | |
| SCHEMBL28045695 | 0.76 | CTSK (0.34) | EPHX1CTSKTAAR1CYP1A2MEN1 | |
| SCHEMBL28039334 | 0.74 | CTSK (0.32) | CTSKCTSLCTSB | |
| SCHEMBL28113598 | 0.74 | CTSK (0.34) | EPHX1CTSKTAAR1CYP1A2MEN1 | |
| SCHEMBL28103059 | 0.74 | CTSK (0.34) | EPHX1CTSKTAAR1CYP1A2MEN1 | |
| SCHEMBL28126964 | 0.72 | — | — | |
| SCHEMBL12630161 | 0.70 | ACE (0.44) | EPHX1CTSKTAAR1CYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102803252-B | Be used for the treatment of indole amides derivative and the related compound thereof of neurodegenerative disorders | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2016-05-25 | — | — | CN | disclosed |