Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.34 |
| ▸ | CTSB | P07858 | 2/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | CTSH | P09668 | 1/20 | 0.31 |
| ▸ | CPA1 | P15085 | 1/20 | 0.31 |
| ▸ | LAP3 | P28838 | 4/20 | 0.30 |
| ▸ | ANPEP | P15144 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28045792 | 0.85 | MAOA (0.36) | CYP1A2 | |
| SCHEMBL18085416 | 0.80 | EPHX1 (0.48) | CTSKCTSLCTSBEPHX1MEN1 | |
| SCHEMBL28061404 | 0.79 | EPHX1 (0.35) | CTSKCTSLCTSBEPHX1MEN1 | |
| SCHEMBL28045730 | 0.77 | CTSK (0.37) | CTSKCTSLCTSBEPHX1MEN1 | |
| SCHEMBL28052170 | 0.76 | KLKB1 (0.35) | — | |
| SCHEMBL18065072 | 0.76 | — | — | |
| SCHEMBL15072037 | 0.73 | — | — | |
| SCHEMBL28113598 | 0.73 | CTSK (0.34) | CTSKCTSLCTSBEPHX1MEN1 | |
| SCHEMBL27698547 | 0.73 | PNP (0.36) | CTSKEPHX1CPA1CYP1A2 | |
| SCHEMBL31690300 | 0.72 | CYP1A2 (0.61) | CPA1ANPEPCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105829317-B | Imidazopyrazines ketone derivatives | 默克专利股份公司 | 2019-03-29 | — | — | CN | disclosed |
| CN-105829317-A | Imidazopyrazinone derivatives | 默克专利股份公司 | 2016-08-03 | — | — | CN | disclosed |