Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | AKT2 | P31751 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28061544 | 0.80 | LMNA (0.39) | — | |
| SCHEMBL28061589 | 0.75 | SLC6A3 (0.35) | — | |
| SCHEMBL28061570 | 0.72 | EPHX2 (0.33) | — | |
| SCHEMBL28061573 | 0.72 | ALDH1A1 (0.41) | MEN1KMT2A | |
| SCHEMBL327190 | 0.71 | KCNA3 (0.39) | MEN1KMT2A | |
| SCHEMBL28061554 | 0.71 | SLC6A4 (0.38) | CYP1A2 | |
| SCHEMBL28128976 | 0.69 | MEN1 (0.35) | MEN1KMT2A | |
| SCHEMBL28793420 | 0.67 | — | — | |
| SCHEMBL21268313 | 0.67 | EPHX2 (0.32) | — | |
| SCHEMBL3542512 | 0.67 | EPHX2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105693645-B | Condensed heterocyclic compouds as ion channel modulators | 吉利德科学公司 | 2018-10-09 | — | — | CN | disclosed |
| CN-105693645-A | FUSED HETEROCYCLIC COMPOUNDS AS SODIUM CHANNEL MODULATORS | 吉利德科学公司 | 2016-06-22 | — | — | CN | disclosed |
| CN-103649056-B | Fused heterocyclic compounds as modulators of ion channels | GILEAD SCIENCES, INC. (US) | 2016-04-27 | — | — | CN | disclosed |