Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.35 |
| ▸ | DRD2 | P14416 | 4/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28061573 | 0.90 | ALDH1A1 (0.41) | SLC6A3DRD2SLC6A2SLC6A4LMNA | |
| SCHEMBL28061570 | 0.90 | EPHX2 (0.33) | — | |
| SCHEMBL28061544 | 0.81 | LMNA (0.39) | LMNA | |
| SCHEMBL28061552 | 0.79 | LMNA (0.31) | SLC6A3SLC6A2SLC6A4LMNA | |
| SCHEMBL28061564 | 0.75 | LIPE (0.35) | — | |
| SCHEMBL28001641 | 0.69 | SLC6A4 (0.41) | SLC6A3SLC6A2CYP2D6SLC6A4LMNA | |
| SCHEMBL3542512 | 0.68 | EPHX2 (0.32) | — | |
| SCHEMBL21268313 | 0.68 | EPHX2 (0.32) | — | |
| SCHEMBL28793420 | 0.68 | — | — | |
| SCHEMBL16951433 | 0.66 | CTSS (0.34) | SLC6A3DRD2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105693645-B | Condensed heterocyclic compouds as ion channel modulators | 吉利德科学公司 | 2018-10-09 | — | — | CN | disclosed |
| CN-105693645-A | FUSED HETEROCYCLIC COMPOUNDS AS SODIUM CHANNEL MODULATORS | 吉利德科学公司 | 2016-06-22 | — | — | CN | disclosed |
| CN-103649056-B | Fused heterocyclic compounds as modulators of ion channels | GILEAD SCIENCES, INC. (US) | 2016-04-27 | — | — | CN | disclosed |