Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2691863 | 0.83 | MAPK1 (0.53) | L3MBTL1KDM4ETSHRRAB9ALMNA | |
| SCHEMBL1856870 | 0.82 | MAPK1 (0.66) | L3MBTL1KDM4ETSHRRAB9ALMNA | |
| SCHEMBL1871973 | 0.81 | HSD17B10 (0.53) | L3MBTL1KDM4ETSHRGLARAB9A | |
| SCHEMBL3197513 | 0.78 | RAB9A (0.51) | L3MBTL1KDM4ETSHRRAB9ALMNA | |
| SCHEMBL25839509 | 0.78 | L3MBTL1 (0.62) | L3MBTL1KDM4ETSHRGLARAB9A | |
| SCHEMBL17407599 | 0.77 | KMT2A (0.48) | L3MBTL1KDM4ETSHRRAB9ALMNA | |
| SCHEMBL5176902 | 0.77 | PLOD2 (0.53) | L3MBTL1KDM4ELMNAADRB2ADRB1 | |
| SCHEMBL14081911 | 0.76 | ADRB2 (0.55) | L3MBTL1KDM4ETSHRGLARAB9A | |
| SCHEMBL12157882 | 0.75 | PLOD2 (0.44) | L3MBTL1KDM4ELMNAKMT2AMEN1 | |
| SCHEMBL12398855 | 0.75 | KMT2A (0.46) | L3MBTL1TSHRKMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105685064-A | HERBICIDAL ISOXAZOLO[5,4-b]PYRIDINES | 巴斯夫欧洲公司 | 2016-06-22 | — | — | CN | claimed |
| CN-103124733-B | Herbicidal isoxazolo [5,4-b ] pyridines | BASF SE (DE) | 2016-03-30 | — | — | CN | claimed |
| CN-105685064-A | HERBICIDAL ISOXAZOLO[5,4-b]PYRIDINES | 巴斯夫欧洲公司 | 2016-06-22 | — | — | CN | disclosed |
| CN-103124733-B | Herbicidal isoxazolo [5,4-b ] pyridines | BASF SE (DE) | 2016-03-30 | — | — | CN | disclosed |