SCHEMBL28062335

SCHEMBL28062335

C#CC[C@@H]([C@H](O)c1cc(F)c(F)cc1F)N(C(=O)O)C(C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28062336 1.00 MAOA (0.32) MAOAMAOB
SCHEMBL28037292 0.87 CES2 (0.36) MAOAMAOB
SCHEMBL28037291 0.87 CES2 (0.36) MAOAMAOB
SCHEMBL28062609 0.73 POLB (0.31) MAOAMAOB
SCHEMBL18760097 0.69
SCHEMBL17380485 0.68 TRPA1 (0.39)
SCHEMBL17102154 0.66 CES2 (0.40)
SCHEMBL15611672 0.65
SCHEMBL15611673 0.65
SCHEMBL14965960 0.64 AOC3 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105531277-A Pyrrolo-imidazole ring derivatives and their use in medicine SICHUAN HAISCO PHARMACEUTICAL CO LTD 2016-04-27 CN disclosed
CN-105518008-A Amino pyranoid ring derivative and composition and use thereof SICHUAN HAISCO PHARMACEUTICAL CO LTD 2016-04-20 CN disclosed