Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17102154 | 0.86 | CES2 (0.40) | — | |
| SCHEMBL28062336 | 0.73 | MAOA (0.32) | MAOAMAOB | |
| SCHEMBL28062335 | 0.73 | MAOA (0.32) | MAOAMAOB | |
| SCHEMBL18760099 | 0.69 | — | — | |
| SCHEMBL17865487 | 0.67 | CES2 (0.40) | — | |
| SCHEMBL28037292 | 0.66 | CES2 (0.36) | MAOAMAOB | |
| SCHEMBL28037291 | 0.66 | CES2 (0.36) | MAOAMAOB | |
| SCHEMBL17373217 | 0.66 | — | — | |
| SCHEMBL28044516 | 0.66 | — | — | |
| SCHEMBL16993854 | 0.64 | GRIK1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105518008-B | Amino pyrans ring derivatives and combinations thereof and application | 海思科医药集团股份有限公司 | 2018-03-27 | — | — | CN | disclosed |
| CN-105531277-B | Pyrrolo-imidazole ring derivatives and their use in medicine | 四川海思科制药有限公司 | 2018-03-02 | — | — | CN | disclosed |
| CN-105531277-A | Pyrrolo-imidazole ring derivatives and their use in medicine | SICHUAN HAISCO PHARMACEUTICAL CO LTD | 2016-04-27 | — | — | CN | disclosed |
| CN-105518008-A | Amino pyranoid ring derivative and composition and use thereof | SICHUAN HAISCO PHARMACEUTICAL CO LTD | 2016-04-20 | — | — | CN | disclosed |