Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.59 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Enterodiol SCHEMBL31171980 | 0.87 | ENPP2 (0.52) | OPRK1CYP2D6SLC6A2ALOX15CYP3A4 | |
| Enterodiol SCHEMBL30334906 | 0.87 | ENPP2 (0.52) | OPRK1CYP2D6SLC6A2ALOX15CYP3A4 | |
| Enterodiol SCHEMBL11271740 | 0.87 | ENPP2 (0.52) | OPRK1CYP2D6SLC6A2ALOX15CYP3A4 | |
| Enterodiol SCHEMBL120183 | 0.87 | ENPP2 (0.52) | OPRK1CYP2D6SLC6A2ALOX15CYP3A4 | |
| Enterodiol SCHEMBL2641390 | 0.87 | ENPP2 (0.52) | OPRK1CYP2D6SLC6A2ALOX15CYP3A4 | |
| Enterodiol SCHEMBL31171979 | 0.87 | ENPP2 (0.52) | OPRK1CYP2D6SLC6A2ALOX15CYP3A4 | |
| Enterodiol SCHEMBL31171993 | 0.87 | ENPP2 (0.52) | OPRK1CYP2D6SLC6A2ALOX15CYP3A4 | |
| SCHEMBL4531632 | 0.85 | ALOX15 (0.55) | TRPA1OPRK1OPRM1OPRD1CYP2D6 | |
| Enterodiol SCHEMBL2987870 | 0.83 | OPRK1 (0.52) | OPRK1OPRM1OPRD1CHRM1DRD2 | |
| SCHEMBL1889290 | 0.79 | TRPA1 (0.70) | TRPA1CYP2D6SLC6A2CYP3A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180353441-A1 | COMPOSITIONS AND METHODS FOR TREATING LUNG DISEASES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2018-12-13 | — | — | US | claimed |
| US-20110300247-A1 | FLAXSEED LIGNAN COMPLEX AND ITS USE THEREOF | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2011-12-08 | — | — | US | claimed |
| US-20100239696-A1 | FLAXSEED LIGNAN COMPLEX, METHODS OF USING AMD COMPOSITIONS THEREOF | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2010-09-23 | — | — | US | claimed |
| CN-113845967-A | Method for reducing acid value of sesame product prepared from germinated sesame | 丰益(上海)生物技术研发中心有限公司 | 2021-12-28 | — | — | CN | disclosed |
| US-20180280462-A1 | USE OF FLAXSEED AND FLAXSEED DERIVATIVES FOR TREATMENT OF NEUROLOGICAL DISORDERS AND VIRAL DISEASES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2018-10-04 | — | — | US | disclosed |
| US-9987321-B2 | Use of flaxseed and flaxseed derivatives for treatment of neurological disorders and viral diseases | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2018-06-05 | — | — | US | disclosed |
| US-20140308379-A1 | USE OF FLAXSEED AND FLAXSEED DERIVATIVES FOR TREATMENT OF NEUROLOGICAL DISORDERS AND VIRAL DISEASES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2014-10-16 | — | — | US | disclosed |