Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | RRM1 | P23921 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL577071 | 0.76 | ALDH1A1 (0.53) | MAOASMN1; SMN2HPGDMAPTNPC1 | |
| SCHEMBL30985950 | 0.76 | ALDH1A1 (0.53) | MAOASMN1; SMN2HPGDMAPTNPC1 | |
| SCHEMBL5949941 | 0.76 | LMNA (0.78) | LMNAPTGS1CYP2D6ADRB2ADRB1 | |
| SCHEMBL8681925 | 0.75 | ESR1 (0.44) | ESR1ESR2 | |
| SCHEMBL1618880 | 0.74 | LMNA (1.00) | LMNAMAOAPTGS1KMT2ACYP2D6 | |
| SCHEMBL2943775 | 0.74 | LMNA (1.00) | LMNAMAOAPTGS1KMT2ACYP2D6 | |
| SCHEMBL50453 | 0.74 | LMNA (1.00) | LMNAMAOAPTGS1KMT2ACYP2D6 | |
| SCHEMBL3254859 | 0.74 | LMNA (1.00) | LMNAMAOAPTGS1KMT2ACYP2D6 | |
| SCHEMBL8686830 | 0.74 | ESR1 (0.43) | ESR1ESR2 | |
| SCHEMBL577600 | 0.74 | PRKAB2 (0.37) | RRM1MAOASMN1; SMN2POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2180014-B1 | Method for producing thermoplastic resin, polyester resin and polycarbonate resin, and their applications | MITSUBISHI GAS CHEMICAL CO (JP) | 2011-12-14 | — | — | EP | disclosed |
| EP-2180014-A1 | Method for producing thermoplastic resin, polyester resin and polycarbonate resin, and their applications | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2010-04-28 | — | — | EP | disclosed |