SCHEMBL8681925

SCHEMBL8681925

OCCCOc1ccc(C2c3ccccc3-c3ccccc32)cc1

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44
ALDH1A1 P00352 1/20 0.43
RECQL P46063 1/20 0.43
PDK2 Q15119 4/20 0.42
GPR174 Q9BXC1 1/20 0.40
FFAR4 Q5NUL3 2/20 0.40
PTPN1 P18031 1/20 0.39
KCNA3 P22001 1/20 0.38
GAA P10253 1/20 0.38
HRH3 Q9Y5N1 2/20 0.38
LTA4H P09960 1/20 0.37
EPHX2 P34913 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8686830 0.95 ESR1 (0.43) ESR1ESR2ALDH1A1RECQLPDK2
SCHEMBL30985950 0.92 ALDH1A1 (0.53) ESR1ESR2ALDH1A1RECQLPDK2
SCHEMBL577071 0.92 ALDH1A1 (0.53) ESR1ESR2ALDH1A1RECQLPDK2
SCHEMBL2481498 0.89 ESR1 (0.41) ESR1ESR2ALDH1A1RECQLPDK2
SCHEMBL4272491 0.84 ESR1 (0.45) ESR1ESR2ALDH1A1RECQLPDK2
SCHEMBL29586924 0.83 ALDH1A1 (0.44) ESR1ESR2ALDH1A1RECQLPDK2
SCHEMBL28233468 0.81 LTA4H (0.53) GPR174GAALTA4H
SCHEMBL5796673 0.78 L3MBTL1 (0.42) ESR1ESR2RECQLGPR174LTA4H
SCHEMBL577600 0.76 PRKAB2 (0.37) ESR1ESR2ALDH1A1PDK2HRH3
SCHEMBL2806272 0.75 LMNA (0.57) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5780194-A PHOTOSENSITIVE LAYER OF POLYESTER BINDING RESIN, ELECTRIC CHARGE GENERATING MATERIAL, AND HOLE TRANSFERRING MATERIAL MITA INDUSTRIAL CO., LTD. (JP) 1998-07-14 US disclosed