Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.41 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8681925 | 0.95 | ESR1 (0.44) | ESR1ESR2PDK2ALDH1A1RECQL | |
| SCHEMBL30985950 | 0.90 | ALDH1A1 (0.53) | ESR1ESR2PDK2ALDH1A1RECQL | |
| SCHEMBL577071 | 0.90 | ALDH1A1 (0.53) | ESR1ESR2PDK2ALDH1A1RECQL | |
| SCHEMBL2481498 | 0.85 | ESR1 (0.41) | ESR1ESR2PDK2ALDH1A1RECQL | |
| SCHEMBL28233468 | 0.83 | LTA4H (0.53) | GPR174GAA | |
| SCHEMBL4272491 | 0.82 | ESR1 (0.45) | ESR1ESR2PDK2ALDH1A1RECQL | |
| SCHEMBL29586924 | 0.81 | ALDH1A1 (0.44) | ESR1ESR2PDK2ALDH1A1RECQL | |
| SCHEMBL5796673 | 0.77 | L3MBTL1 (0.42) | ESR1ESR2RECQLGPR174 | |
| SCHEMBL10731573 | 0.75 | KCNA3 (0.55) | ALDH1A1RECQLKCNA3PRSS1GAA | |
| SCHEMBL577600 | 0.75 | PRKAB2 (0.37) | ESR1ESR2PDK2ALDH1A1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780194-A | PHOTOSENSITIVE LAYER OF POLYESTER BINDING RESIN, ELECTRIC CHARGE GENERATING MATERIAL, AND HOLE TRANSFERRING MATERIAL | MITA INDUSTRIAL CO., LTD. (JP) | 1998-07-14 | — | — | US | disclosed |