SCHEMBL28062748

SCHEMBL28062748

CC(C)(C)O[SiH2]c1cccc(Cl)c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.34
TSHR P16473 1/20 0.34
RIPK1 Q13546 1/20 0.33
PGR P06401 1/20 0.33
CYP3A4 P08684 2/20 0.32
IDO1 P14902 2/20 0.32
AGXT P21549 2/20 0.32
SLC6A2 P23975 4/20 0.32
SLC6A4 P31645 3/20 0.32
SLC6A3 Q01959 3/20 0.32
AOC3 Q16853 1/20 0.32
CHRNA1 P02708 1/20 0.32
CHRNG P07510 1/20 0.32
ITGA5 P08648 1/20 0.32
CHRNB1 P11230 1/20 0.32
CHRNB2 P17787 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
CYP2C19 P33261 1/20 0.32
HRH1 P35367 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2950779 0.86
SCHEMBL28062829 0.84 RIPK1 (0.39) ALDH1A1TSHRRIPK1CYP3A4IDO1
SCHEMBL27959494 0.77 ACHE (0.39) ALDH1A1RIPK1IDO1AGXTAOC3
SCHEMBL28062865 0.77 ALDH1A1 (0.39) ALDH1A1RIPK1IDO1AGXTTAAR1
SCHEMBL28062827 0.75 MEN1 (0.38) TSHRCYP3A4SLC6A2SLC6A4SLC6A3
SCHEMBL715568 0.74 MAPK1 (0.37) ALDH1A1TSHRSLC6A2AOC3TAAR1
SCHEMBL23493467 0.73 TP53 (0.44) ALDH1A1TSHR
SCHEMBL23493432 0.72 ALDH1A1 (0.36) ALDH1A1TSHRCYP3A4CYP2C19SMN1; SMN2
SCHEMBL704585 0.71
SCHEMBL27959398 0.71 RIPK1 (0.34) RIPK1SLC6A2SLC6A3CHRNA1CHRNG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105555901-A Polishing composition FUJIMI INC 2016-05-04 CN disclosed