Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | GFER | P55789 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL99032 | 0.87 | ALDH1A1 (0.69) | ALDH1A1MAOAMAOBLMNANPC1 | |
| SCHEMBL28260866 | 0.82 | ALDH1A1 (0.62) | ALDH1A1MAOAMAOBNPC1RAB9A | |
| SCHEMBL1375430 | 0.79 | LMNA (0.73) | ALDH1A1LMNANPC1RAB9ATP53 | |
| SCHEMBL628551 | 0.77 | ALDH1A1 (0.58) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23220843 | 0.75 | KMT2A (0.61) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL149502 | 0.75 | KMT2A (0.61) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23220824 | 0.75 | KMT2A (0.61) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11896426 | 0.74 | NFE2L2 (0.57) | ALDH1A1MAOAMAOBMAPTKMT2A | |
| SCHEMBL11896428 | 0.74 | NFE2L2 (0.57) | ALDH1A1MAOAMAOBMAPTKMT2A | |
| SCHEMBL29403339 | 0.74 | NFE2L2 (0.57) | ALDH1A1MAOAMAOBMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105622431-A | Stilbene analogs and methods of treating cancer | UNIV KENTUCKY | 2016-06-01 | — | — | CN | claimed |
| CN-105622431-A | Stilbene analogs and methods of treating cancer | UNIV KENTUCKY | 2016-06-01 | — | — | CN | disclosed |