SCHEMBL28063223

SCHEMBL28063223

CCC[SiH2]OC(=O)CCC(C1CCCC1)C1CCCC1

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.35
NAAA Q02083 2/20 0.33
CTSK P43235 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28063122 0.91 NAAA (0.38) SMN1; SMN2NAAACTSK
SCHEMBL28063224 0.78 ALDH1A1 (0.38) NAAA
SCHEMBL28063124 0.75 NAAA (0.45) SMN1; SMN2NAAA
SCHEMBL28063132 0.72 ALDH1A1 (0.50)
SCHEMBL4654383 0.70 EPHX1 (0.46) SMN1; SMN2
SCHEMBL28063263 0.69 CES1 (0.42)
SCHEMBL28063178 0.69 LMNA (0.40)
SCHEMBL28063140 0.69 LMNA (0.40)
SCHEMBL3037218 0.68 EPHX1 (0.50) SMN1; SMN2
SCHEMBL10582810 0.68 EPHX1 (0.50) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103391947-B Stabilization of polymers containing hydrolyzable functional groups 株式会社普利司通 2016-08-24 CN disclosed