SCHEMBL28063122

SCHEMBL28063122

CCC[SiH2]OC(=O)CCCC(C1CCCC1)C1CCCC1

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.33
PREP P48147 3/20 0.32
EPHX2 P34913 2/20 0.32
LMNA P02545 2/20 0.32
CTSK P43235 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28063223 0.91 SMN1; SMN2 (0.35) NAAASMN1; SMN2CTSK
SCHEMBL28063124 0.79 NAAA (0.45) NAAASMN1; SMN2EPHX2LMNA
SCHEMBL28063224 0.75 ALDH1A1 (0.38) NAAA
SCHEMBL28063263 0.74 CES1 (0.42) LMNATSHR
SCHEMBL28063226 0.73 LMNA (0.42) LMNATSHR
SCHEMBL9957937 0.72 ALDH1A1 (0.43) NAAAEPHX2TSHR
SCHEMBL28063132 0.70 ALDH1A1 (0.50) LMNATSHR
SCHEMBL4655283 0.68 EPHX1 (0.42) LMNATSHR
SCHEMBL4654383 0.68 EPHX1 (0.46) SMN1; SMN2LMNATSHR
SCHEMBL6658190 0.67 DGKA (0.42) NAAALMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103391947-B Stabilization of polymers containing hydrolyzable functional groups 株式会社普利司通 2016-08-24 CN disclosed