SCHEMBL2806369

SCHEMBL2806369

O=C(O)C1NCCNC1C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A2 P43004 2/20 0.59
MEN1 O00255 1/20 0.54
BLM P54132 1/20 0.54
KMT2A Q03164 1/20 0.54
PKM P14618 1/20 0.44
ALDH1A1 P00352 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C19 P33261 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
ARG1 P05089 5/20 0.42
ARG2 P78540 1/20 0.42
TSHR P16473 2/20 0.39
GABRP O00591 1/20 0.39
GABRD O14764 1/20 0.39
GABRA1 P14867 1/20 0.39
GABRB1 P18505 1/20 0.39
GABRG2 P18507 1/20 0.39
GABRB3 P28472 1/20 0.39
GABRA5 P31644 1/20 0.39
GABRA3 P34903 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2806367 1.00 SLC1A2 (0.59) SLC1A2MEN1BLMKMT2APKM
SCHEMBL11511876 1.00 SLC1A2 (0.59) SLC1A2MEN1BLMKMT2APKM
SCHEMBL11511873 1.00 SLC1A2 (0.59) SLC1A2MEN1BLMKMT2APKM
SCHEMBL7322888 0.81 SLC1A2 (0.48) SLC1A2MEN1BLMKMT2APKM
SCHEMBL28948796 0.81 SLC1A2 (0.43) SLC1A2MEN1BLMKMT2APKM
SCHEMBL11107498 0.80 SLC1A2 (0.46) SLC1A2MEN1BLMKMT2APKM
SCHEMBL9511237 0.76 SLC1A2 (0.39) SLC1A2MEN1BLMKMT2AALDH1A1
SCHEMBL4339884 0.75 SLC1A2 (0.43) SLC1A2MEN1BLMKMT2APKM
SCHEMBL4332743 0.75 SLC1A2 (0.43) SLC1A2MEN1BLMKMT2AALDH1A1
SCHEMBL1364961 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108269991-A Preparation method of zinc-bismuth alloy powder for flexible battery cathode 上海移宇科技股份有限公司 2018-07-10 CN claimed
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US claimed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US claimed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US claimed
CN-1675595-A Use of salts of layered double hydroxides CLARIANT GMBH (DE) 2005-09-28 CN claimed
EP-1529247-A1 USE OF SALTS OF LAYERED DOUBLE HYDROXIDES Clariant GmbH (DE) 2005-05-11 EP claimed
WO-2004019138-A1 USE OF SALTS OF LAYERED DOUBLE HYDROXIDES CLARIANT GMBH (DE) 2004-03-04 WO claimed
US-20250092395-A1 A GLUN2D INHIBITOR FOR USE IN THE TREATMENT OR RELAPSE PREVENTION OF A DEPRESSIVE EPISODE ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) 2025-03-20 US disclosed
EP-4469042-A1 A GLUN2D INHIBITOR FOR USE IN THE TREATMENT OR RELAPSE PREVENTION OF A DEPRESSIVE EPISODE Albert-Ludwigs-Universität Freiburg (DE) 2024-12-04 EP disclosed
CN-118785903-A GLUN2D inhibitors for the treatment or relapse prevention of depressive episodes 阿尔伯特-路德维希-弗莱堡大学 2024-10-15 CN disclosed
WO-2023144163-A1 A GLUN2D INHIBITOR FOR USE IN THE TREATMENT OR RELAPSE PREVENTION OF A DEPRESSIVE EPISODE ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) 2023-08-03 WO disclosed
EP-4217071-A1 TRICYCLIC PYRIDONES AND PYRIMIDONES Erasca, Inc. (US) 2023-08-02 EP disclosed
EP-4204100-A1 HAIR LIGHTENING COMPOSITIONS PROVIDING DAMAGE PROTECTION AND SENSORIAL BENEFITS AND METHODS OF USE L'OREAL (FR) 2023-07-05 EP disclosed
EP-0655656-A1 Toner for developing electrostatic image TOMOEGAWA PAPER CO. LTD. (JP) 1995-05-31 EP disclosed
US-5399693-A Substituted piperazine-2-carboxylic acids and derivatives thereof BRITISH TECHNOLOGY GROUP LIMITED (GB) 1995-03-21 US disclosed
EP-0617337-A2 Toner for developing electrostatic image TOMOEGAWA PAPER CO. LTD. (JP) 1994-09-28 EP disclosed
EP-0159889-B1 4-SUBSTITUTED PIPERAZINE-2-CARBOXYLIC ACIDS PROCESS AND PHARMACEUTICAL COMPOSITIONS BTG INTERNATIONAL LIMITED (GB) 1992-09-30 EP disclosed
EP-0159889-A2 4-Substituted piperazine-2-carboxylic acids process and pharmaceutical compositions BTG INTERNATIONAL LIMITED (GB) 1985-10-30 EP disclosed
US-4142061-A FOR STABILIZING COBALT CABONYL CATALYST CHEVRON RESEARCH COMPANY (US) 1979-02-27 US disclosed
US-4096191-A Hydroformylation of olefins using azoxy-dentated ligands CHEVRON RESEARCH COMPANY (US) 1978-06-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250092395-A1 A GLUN2D INHIBITOR FOR USE IN THE TREATMENT OR RELAPSE PREVENTION OF A DEPRESSIVE EPISODE GRIN2A, GRIN2B, GRIN2C SLC1A2 27/4885MEN1 4780/4885BLM 4358/4885
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS CUTA, SUCLG1, KRT18 SLC1A2 4244/4885MEN1 2029/4885BLM 3099/4885
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT ACMSD, CUTA, PCCA SLC1A2 3491/4885MEN1 748/4885BLM 1845/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.