SCHEMBL2806367

SCHEMBL2806367

O=C(O)[C@H]1NCCN[C@H]1C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A2 P43004 2/20 0.59
MEN1 O00255 1/20 0.54
BLM P54132 1/20 0.54
KMT2A Q03164 1/20 0.54
PKM P14618 1/20 0.44
ALDH1A1 P00352 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C19 P33261 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
ARG1 P05089 5/20 0.42
ARG2 P78540 1/20 0.42
TSHR P16473 2/20 0.39
GABRP O00591 1/20 0.39
GABRD O14764 1/20 0.39
GABRA1 P14867 1/20 0.39
GABRB1 P18505 1/20 0.39
GABRG2 P18507 1/20 0.39
GABRB3 P28472 1/20 0.39
GABRA5 P31644 1/20 0.39
GABRA3 P34903 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11511876 1.00 SLC1A2 (0.59) SLC1A2MEN1BLMKMT2APKM
SCHEMBL11511873 1.00 SLC1A2 (0.59) SLC1A2MEN1BLMKMT2APKM
SCHEMBL2806369 1.00 SLC1A2 (0.59) SLC1A2MEN1BLMKMT2APKM
SCHEMBL7322888 0.81 SLC1A2 (0.48) SLC1A2MEN1BLMKMT2APKM
SCHEMBL28948796 0.81 SLC1A2 (0.43) SLC1A2MEN1BLMKMT2APKM
SCHEMBL11107498 0.80 SLC1A2 (0.46) SLC1A2MEN1BLMKMT2APKM
SCHEMBL9511237 0.76 SLC1A2 (0.39) SLC1A2MEN1BLMKMT2AALDH1A1
SCHEMBL4339884 0.75 SLC1A2 (0.43) SLC1A2MEN1BLMKMT2APKM
SCHEMBL4332743 0.75 SLC1A2 (0.43) SLC1A2MEN1BLMKMT2AALDH1A1
SCHEMBL1364961 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US claimed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US claimed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US claimed
EP-4204100-A1 HAIR LIGHTENING COMPOSITIONS PROVIDING DAMAGE PROTECTION AND SENSORIAL BENEFITS AND METHODS OF USE L'OREAL (FR) 2023-07-05 EP disclosed
CN-116322616-A Hair lightening compositions providing damage protection and sensory benefits and methods of use 欧莱雅 2023-06-23 CN disclosed
US-11559474-B2 Hair lightening compositions and methods of use L'OREAL (FR) 2023-01-24 US disclosed
WO-2022047081-A1 HAIR LIGHTENING COMPOSITIONS PROVIDING DAMAGE PROTECTION AND SENSORIAL BENEFITS AND METHODS OF USE HENRY DEREK (US) 2022-03-03 WO disclosed
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US disclosed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US disclosed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US disclosed
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION L'OREAL (FR) 2009-01-29 US disclosed
US-6916816-B2 Phenanthryl piperazinyl dicarboxylic acids as selective NMDA receptor modulating agents THE BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) 2005-07-12 US disclosed
EP-1244638-B1 PHENANTHRYL PIPERAZINYL DICARBOXYLIC ACIDS AS SELECTIVE NMDA RECEPTOR MODULATING AGENTS UNIV BRISTOL (GB) 2004-05-12 EP disclosed
US-20030078237-A1 Phenanthryl piperazinyl dicarboxylic acids as selective nmda receptor modulating agents US ARMY, SECRETARY OF THE ARMY 2003-04-24 US disclosed
EP-1244638-A2 PHENANTHRYL PIPERAZINYL DICARBOXYLIC ACIDS AS SELECTIVE NMDA RECEPTOR MODULATING AGENTS UNIVERSITY OF NEBRASKA BOARD OF REGENTS (US) 2002-10-02 EP disclosed
WO-2001044205-A2 PHENANTHRYL PIPERAZINYL DICARBOXYLIC ACIDS AS SELECTIVE NMDA RECEPTOR MODULATING AGENTS UNIVERSITY OF NEBRASKA BOARD OF REGENTS (US) 2001-06-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030078237-A1 Phenanthryl piperazinyl dicarboxylic acids as selective nmda receptor modulating agents GRIK2, GRIK3, GRIK5 SLC1A2 41/4885MEN1 2241/4885BLM 4584/4885
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS CUTA, SUCLG1, KRT18 SLC1A2 4244/4885MEN1 2029/4885BLM 3099/4885
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION CUTA, SYMPK, TPRKB SLC1A2 4811/4885MEN1 452/4885BLM 350/4885
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT ACMSD, CUTA, PCCA SLC1A2 3491/4885MEN1 748/4885BLM 1845/4885
US-11559474-B2 Hair lightening compositions and methods of use TYR, ALAD, CYBA SLC1A2 333/4885MEN1 2921/4885BLM 1518/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.