Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.37 |
| ▸ | FASN | P49327 | 1/20 | 0.36 |
| ▸ | CDC42BPB | Q9Y5S2 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.35 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | TDO2 | P48775 | 2/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141858 | 0.72 | DRD4 (0.48) | SCD5PROKR1USP30BTK | |
| SCHEMBL6276568 | 0.70 | NPC1 (0.46) | PDE10AMAPK7ALDH1A1 | |
| SCHEMBL1303713 | 0.70 | PDE10A (0.39) | TRPV1PDE10A | |
| SCHEMBL9984684 | 0.70 | PDE10A (0.39) | TRPV1PDE10A | |
| SCHEMBL9988573 | 0.70 | PDE10A (0.43) | SCD5TRPV1PDE10A | |
| SCHEMBL31321221 | 0.69 | GPR119 (0.53) | KDM4E | |
| SCHEMBL28063994 | 0.69 | PDE10A (0.36) | TRPV1PDE10AMAPK7ALDH1A1 | |
| SCHEMBL2596306 | 0.69 | PDE10A (0.40) | TRPV1PDE10A | |
| SCHEMBL9988088 | 0.69 | PDE10A (0.63) | PDE10A | |
| SCHEMBL6644012 | 0.68 | HTR2C (0.40) | PDE10AMAPK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105473554-A | Fused piperidine amides as modulators of ion channels | VERTEX PHARMA | 2016-04-06 | — | — | CN | disclosed |