Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.41 |
| ▸ | TLR2 | O60603 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.38 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.37 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.37 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21879807 | 0.89 | CPB2 (0.53) | SIRT6SIRT1SLC6A5CPB2FOLH1 | |
| SCHEMBL5808679 | 0.88 | SIRT6 (0.56) | SIRT6SIRT1SLC6A5CPB2FOLH1 | |
| SCHEMBL5808675 | 0.88 | SIRT6 (0.56) | SIRT6SIRT1SLC6A5CPB2FOLH1 | |
| SCHEMBL634032 | 0.83 | FOLH1 (0.46) | SIRT6SIRT1SLC6A5CPB2FOLH1 | |
| SCHEMBL6001433 | 0.83 | SIRT6 (0.50) | SIRT6SIRT1NOD1TLR2KMT2A | |
| SCHEMBL6001429 | 0.83 | SIRT6 (0.50) | SIRT6SIRT1NOD1TLR2KMT2A | |
| SCHEMBL28085656 | 0.82 | FOLH1 (0.47) | SIRT6SIRT1SLC6A5CPB2FOLH1 | |
| SCHEMBL7262935 | 0.81 | SLC6A5 (0.62) | SIRT6SIRT1SLC6A5NOD1TLR2 | |
| SCHEMBL8095959 | 0.81 | NOD1 (0.54) | NOD1 | |
| Hydrochloric Acid SCHEMBL10517148 | 0.80 | SLC6A5 (0.60) | SIRT6SIRT1SLC6A5NOD1TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103183725-B | Method for detecting protein lysine crotonyl acylation modification and developing affinity reagent | 杭州景杰生物科技有限公司 | 2016-06-08 | — | — | CN | disclosed |