Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | LOX | P28300 | 1/20 | 0.31 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14680553 | 0.81 | MAPT (0.35) | KDM4EALDH1A1SMN1; SMN2GRM5 | |
| Hydrochloric Acid SCHEMBL28293574 | 0.79 | MAPT (0.34) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL28987042 | 0.79 | SRC (0.33) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL28097358 | 0.77 | SYK (0.36) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7284124 | 0.77 | SRC (0.41) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL25457192 | 0.77 | KDM4E (0.38) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL28065313 | 0.76 | MEN1 (0.33) | ALDH1A1 | |
| SCHEMBL511705 | 0.75 | LOXL2 (0.40) | RECQLLOXLOXL3LOXL2GRM5 | |
| SCHEMBL7284511 | 0.75 | NOS2 (0.54) | KDM4EALDH1A1 | |
| SCHEMBL7284095 | 0.73 | MBOAT4 (0.38) | KDM4EALDH1A1SMN1; SMN2GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104080781-B | 1H-indazole-3-benzamide compound is as the purposes of glycogen synthase kinase 3-beta inhibitors | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2016-05-11 | — | — | CN | disclosed |